Wen Jinxia, Zhao Wenyan, Gao Xu, Ren Xiaofang, Dong Chunping, Wang Cheli, Liu Li, Li Jian
School of Pharmacy, Jiangsu Key Laboratory of Advanced Catalytic Materials and Technology, Changzhou University, Changzhou, 213164, China.
J Org Chem. 2022 Mar 18;87(6):4415-4423. doi: 10.1021/acs.joc.2c00135. Epub 2022 Mar 2.
An efficient synthesis of a variety of [1,2,3]triazolo-[1,5-]quinoxalin-4(5)-ones via a [3 + 2] cyclization reaction by photoredox catalysis between quinoxalinones and hypervalent iodine(III) reagents is reported. A range of quinoxalinones and hypervalent iodine(III) reagents were tolerated well. This cyclization reaction allows access to structurally diverse [1,2,3]triazolo-[1,5-]quinoxalin-4(5)-ones in moderate to good yields.
报道了一种通过喹喔啉酮与高价碘（III）试剂之间的光氧化还原催化[3 + 2]环化反应高效合成多种[1,2,3]三唑并[1,5 - ]喹喔啉 - 4（5） - 酮的方法。一系列喹喔啉酮和高价碘（III）试剂都具有良好的耐受性。这种环化反应能够以中等至良好的产率获得结构多样的[1,2,3]三唑并[1,5 - ]喹喔啉 - 4（5） - 酮。
