Ceska Slov Farm. 2021 Winter;70(6):206-209.
The phytochemical analysis of a methanolic extract from Helichrysum petiolare Hilliard & B. L. (Asteraceae) confirmed the content of phenylpropanoids and flavonoids. Five secondary metabolites were isolated using preparative HPLC, namely coumarin scopolin (1), 3-chlorogenic acid (2), caffeic acid-hexose derivative (3), dicaffeoylquinic acid (5), and the flavonoid isoquercitrin (4). These compounds were identified from this species for the first time. Only dicaffeoylquinic acid was able to inhibit Escherichia coli CCM 7929 at the concertation of 512 μg mL-1 in a screening of antibacterial activity.
从 Helichrysum petiolare Hilliard & B. L.（菊科）的甲醇提取物的植物化学分析中证实了苯丙素类和类黄酮的含量。使用制备高效液相色谱法分离出五种次生代谢产物，分别为香豆素scopolin（1），3-咖啡酸（2），咖啡酰己糖衍生物（3），二咖啡酰奎宁酸（5）和类黄酮异槲皮苷（4）。这些化合物是首次从该物种中鉴定出来的。只有二咖啡酰奎宁酸在对大肠杆菌 CCM 7929 的抑菌活性筛选中，在 512 μg mL-1的浓度下能够抑制其生长。
