正电子发射断层扫描在动脉粥样硬化研究中的应用。
Positron Emission Tomography in Atherosclerosis Research.
机构信息
Turku PET Centre, University of Turku and Turku University Hospital, Turku, Finland.
Turku Center for Disease Modeling, University of Turku, Turku, Finland.
出版信息
Methods Mol Biol. 2022;2419:825-839. doi: 10.1007/978-1-0716-1924-7_50.
Positron emission tomography (PET) is a quantitative imaging technique that uses molecules labeled with positron-emitting radionuclides to visualize and measure biochemical processes in the tissues of living subjects. In recent years, different PET tracers have been evaluated for their ability to characterize the atherosclerotic process in order to study the activity of the disease. Here, we describe detailed PET methods for preclinical studies of atherosclerosis and summarize the key methodological aspects of PET imaging in clinical studies of atherosclerosis.
正电子发射断层扫描（PET）是一种定量成像技术，它使用带有正电子发射放射性核素标记的分子来可视化和测量活体组织中的生化过程。近年来，已经评估了不同的 PET 示踪剂来表征动脉粥样硬化过程的能力，以便研究疾病的活性。在这里，我们描述了动脉粥样硬化的临床前研究的详细 PET 方法，并总结了动脉粥样硬化临床研究中 PET 成像的关键方法学方面。
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