三七中 249 种农药残留的快速测定及膳食摄入风险评估。
Rapid determination and dietary intake risk assessment of 249 pesticide residues in Panax notoginseng.
机构信息
Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming 650500, PR China; Yunnan Provincial Panax Notoginseng Key Laboratory, Kunming 650500, PR China.
National Resource Center for Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, PR China.
出版信息
Ecotoxicol Environ Saf. 2022 Mar 15;233:113348. doi: 10.1016/j.ecoenv.2022.113348. Epub 2022 Feb 28.
UPLC-MS/MS and GC-MS/MS were used to establish a method to simultaneously determine various pesticide residues in Panax notoginseng. Results showed that the limits of detection of 249 pesticides were all 5-10 μg/kg. The detection rate of pesticides in 121 P. notoginseng samples was 93.39%, and 19 pesticides were detected. According to the US Code of Federal Regulations, the Chinese Pharmacopoeia recommended algorithm, and the Japanese "positive list system", the pass rates of pesticide residues were 100%, 99.17%, and 89.26%, respectively. The chronic risk quotient (ADI%) and acute risk quotient (ARfD%) of P. notoginseng were 0.00-0.12% and 0.00-0.15%, respectively. In summary, the detection method established in this study can be used for routine analysis of various P. notoginseng pesticide residues. The pesticide residues in the main root samples of P. notoginseng were at a safe level and unlikely pose health risks to consumers.
超高效液相色谱-串联质谱法（UPLC-MS/MS）和气相色谱-串联质谱法（GC-MS/MS）被用于建立一种可同时测定三七中多种农药残留的方法。结果表明，249 种农药的检出限均为 5-10μg/kg。121 份三七样品中农药的检出率为 93.39%，共检出 19 种农药。根据美国联邦法规法典、《中国药典》推荐算法和日本“肯定列表制度”，农药残留的通过率分别为 100%、99.17%和 89.26%。三七的慢性风险商（ADI%）和急性风险商（ARfD%）分别为 0.00-0.12%和 0.00-0.15%。综上所述，本研究建立的检测方法可用于常规分析三七中的各种农药残留。主根样品中三七的农药残留处于安全水平，不太可能对消费者的健康造成风险。
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