Pachore Javahir A, Shah Vikram Indrajit, Upadhyay Sachin, Shah Kalpesh, Sheth Ashish, Kshatriya Amish
Department of Hip Arthroplasty, Shalby Hospitals, Ahmedabad, Gujarat, India.
Department of Knee, Shalby Hospitals, Ahmedabad, India.
Arthroplasty. 2019 Oct 3;1(1):8. doi: 10.1186/s42836-019-0010-8.
The objective of this study is to share our experience in total hip replacement for the treatment of ochronotic hip arthritis, in particular to report how to establish the diagnosis and some tips to limit complications.
A cohort comprised of 10 patients (12 hips) with alkaptonuric hip arthritis. There were six men and four women with the mean age of 62.80 ± 7.57 years. All patients had a stiff spine, grossly restricted movements of hip joints, and severely limited daily routine activities. Total hip replacement was performed in all patients. The patients were evaluated at 6, 12, and 24 months after surgery, as well as every 4 years thereafter. Harris hip score was used to assess the functional outcome. The level of significance was set at p < 0.05.
The mean follow-up lasted 16.70 ± 6.82 years (3 to 24 years). At the final available follow-up, nine patients returned to work, ambulate without an orthosis, and achieve complete pain relief. Harris hip score was improved from poor to excellent. One patient died 16 years after surgery due to breast cancer. No complication relating to prosthetic failures was detected.
Total hip replacement gives long-term satisfactory results in patients with alkaptonuric hip arthritis, resulting in comparable function of the hips in patients who undergo primary osteoarthrosis.
本研究的目的是分享我们在全髋关节置换治疗褐黄病性髋关节炎方面的经验，特别是报告如何建立诊断以及一些限制并发症的技巧。
一个队列由10例（12髋）褐黄病性髋关节炎患者组成。其中男性6例，女性4例，平均年龄62.80±7.57岁。所有患者均有脊柱僵硬、髋关节活动严重受限以及日常生活活动严重受限。所有患者均接受了全髋关节置换术。在术后6个月、12个月和24个月以及此后每4年对患者进行评估。采用Harris髋关节评分评估功能结果。显著性水平设定为p<0.05。
平均随访时间为16.70±6.82年（3至24年）。在最后一次可获得的随访时，9例患者恢复工作，无需矫形器行走，且疼痛完全缓解。Harris髋关节评分从差改善为优。1例患者术后16年因乳腺癌死亡。未检测到与假体失败相关的并发症。
全髋关节置换术在褐黄病性髋关节炎患者中可获得长期满意的结果，使接受手术的患者髋关节功能与原发性骨关节炎患者相当。
