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80 岁以上患者腰椎管狭窄的手术治疗:风险是否增加?

Surgical management of lumbar spinal stenosis in patients over 80: is there an increased risk?

机构信息

Department of Neurosurgery, Caen University Hospital, Avenue de La Côte de Nacre, 14000, Caen, France.

Unité de Biostatistique Et Recherche Clinique (UBRC), Avenue de la Côte de Nacre, 14000, Caen, France.

出版信息

Neurosurg Rev. 2022 Jun;45(3):2385-2399. doi: 10.1007/s10143-022-01756-w. Epub 2022 Mar 3.

Abstract

Management of lumbar spinal stenosis (LSS) represents the first cause of spinal surgery for the elderly and will increase with the aging population. Although the surgery improves quality of life, the procedure involves anaesthetic and operative risks. The aim of this study was to assess whether the postoperative complication rate was higher for elderly patients and to find confounding factors. We conducted a retrospective study including all LSS surgeries between 2012 and 2020 at the University Hospital of Caen. We compared two populations opposing patients aged over 80 with others. The primary endpoint was the occurrence of a severe complication (SC). Minor complications were the secondary endpoint. Comorbidities, history of lumbar spine surgery and surgical characteristics were recorded. Nine hundred ninety-six patients undergoing surgery for degenerative LSS were identified. Patients over 80 were significantly affected by additional comorbidities: hypertension, heart diseases, higher age-adjusted comorbidity Charlson score, ASA score and use of anticoagulants. Knee-chest position was preferred for younger patients. Older patients underwent a more extensive decompression and had more incidental durotomies. Of the patients, 5.2% presented SC. Age over 80 did not appear to be a significant risk factor for SC, but minor complications increased. Multivariate analysis showed that heart diseases, history of laminectomy, AA-CCI and accidental durotomies were independent risk factors for SC. Surgical management for lumbar spinal stenosis is not associated to a higher rate of severe complications for patients over 80 years of age. However, preoperative risk factors should be investigated to warn the elderly patients that the complication risk is increased although an optimal preparation is the way to avoid them.

摘要

腰椎管狭窄症(LSS)的治疗是老年人脊柱手术的首要原因,并且随着人口老龄化,这一数字还将增加。尽管手术可以提高生活质量,但手术本身存在麻醉和手术风险。本研究旨在评估老年患者术后并发症发生率是否更高,并寻找混杂因素。我们进行了一项回顾性研究,纳入了 2012 年至 2020 年在卡昂大学医院进行的所有 LSS 手术。我们将患者分为两组:年龄超过 80 岁的患者和其他患者。主要终点是严重并发症(SC)的发生。次要终点是轻微并发症。记录了合并症、腰椎手术史和手术特征。共确定了 996 例退行性 LSS 手术患者。80 岁以上的患者合并症明显更多:高血压、心脏病、年龄调整 Charlson 合并症评分更高、ASA 评分和抗凝剂的使用。年轻患者更喜欢采用膝胸位。年长患者接受了更广泛的减压,并且更有可能出现意外的硬脊膜撕裂。患者中有 5.2%出现 SC。年龄超过 80 岁似乎不是 SC 的显著危险因素,但轻微并发症的发生率增加。多变量分析显示,心脏病、椎板切除术史、AA-CCI 和意外硬脊膜撕裂是 SC 的独立危险因素。对于 80 岁以上的患者,腰椎管狭窄症的手术治疗并不与严重并发症发生率增加相关。但是,应调查术前危险因素,以告知老年患者并发症风险增加,尽管最佳准备是避免这些风险的方法。

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