Division of Oral and Maxillofacial Surgery, Tri-Service General Hospital, No. 325, Cheng-Kung Rd., Sec. 2, Neihu District, Taipei City, 11490, Taiwan, ROC.
School of Dentistry, National Defense Medical Center, No. 161, Sec. 6, Minquan E. Rd., Neihu Dist., Taipei City, 11490, Taiwan, ROC.
BMC Oral Health. 2022 Mar 4;22(1):56. doi: 10.1186/s12903-022-02084-7.
The study aimed to investigate the association between socioeconomic status and severity of oral epithelial dysplasia (OED) using current data from the Taiwanese Nationwide Oral Mucosal Screening Program (TNOMSP).
This retrospective analysis was conducted in the Department of Oral and Maxillofacial Surgery at a general hospital in Taipei, Taiwan. A total of 134 participants were analysed from a previous study database of 150 patients. The inclusion criteria included age > 20 years and a history of either tobacco or betel nut use. Background information, including para-habits such as betel and tobacco use, was analysed using the Pearson chi-square (χ) test; furthermore, the correlation of background information with OED severity was investigated using logistic regression (mild or moderate/severe).
High school education level (P < 0.001), poor self-awareness (P = 0.002), current betel use (P < 0.001), and tobacco use (P = 0.003) were highly correlated with moderate- and severe OED (P < 0.05). The odds ratio (OR) of education status above senior high school was 0.03 (95% confidence interval [CI] 0.01-0.15, P < 0.001), while that of junior high school was 1. Current betel chewing (OR 6.57 [95% CI 1.17-37.0], P = 0.033) was significantly associated with OED severity compared with never or ex-use of betel.
We found a strong correlation between the severity of OED and current betel use and low education status. The current study revealed that the socioeconomic status, poor self-awareness, and para-habit history of the patients with OED should be evaluated to identify high-risk individuals using TNOMSP.
本研究旨在利用当前来自台湾全国口腔黏膜筛检计划（TNOMSP）的资料，探讨社会经济地位与口腔上皮异型增生（OED）严重程度之间的关联。
本回顾性分析在台北一家综合医院的口腔颌面外科进行。从先前一项包含 150 名患者的研究资料库中，共分析了 134 名参与者。纳入标准为年龄＞20 岁且有嚼食槟榔或吸烟史。使用皮尔逊卡方（χ）检验分析背景资料，包括嚼食槟榔和吸烟等副习惯；此外，使用逻辑回归（轻度或中度/重度）探讨背景资料与 OED 严重程度的相关性。
高中以上教育程度（P＜0.001）、自我警觉性差（P=0.002）、当前嚼食槟榔（P＜0.001）和吸烟（P=0.003）与中重度 OED 高度相关（P＜0.05）。高中以上教育程度的优势比（OR）为 0.03（95%置信区间 [CI] 0.01-0.15，P＜0.001），而初中为 1。当前嚼食槟榔（OR 6.57 [95% CI 1.17-37.0]，P=0.033）与从不或曾嚼食槟榔相比，与 OED 严重程度显著相关。
我们发现 OED 严重程度与当前嚼食槟榔和低教育程度之间存在很强的相关性。本研究表明，应通过 TNOMSP 评估 OED 患者的社会经济地位、自我警觉性和副习惯史，以识别高危个体。
