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PHYSIOPATHOLOGICAL CHANGES IN PRIMARY ACUTE BLOOD-TRANSMITTED MALARIA AND BABESIA INFECTIONS. II. A COMPARATIVE STUDY OF SERUM-PROTEIN LEVELS IN INFECTED RHESUS MONKEYS, MICE AND PUPPIES.原发性急性血源性疟疾和巴贝斯虫感染的病理生理变化。II. 感染恒河猴、小鼠和幼犬血清蛋白水平的比较研究。
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ALTERATIONS IN SERUM PROTEINS AND 19S ANTIBODY PRODUCTION DURING THE COURSE OF INDUCED MALARIAL INFECTIONS IN MAN.人类诱发疟疾感染过程中血清蛋白和19S抗体产生的变化
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An extension of the 51Cr-release assay for the estimation of mouse cytotoxins.用于估计小鼠细胞毒素的51铬释放试验的扩展。
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Further improvements in the plaque technique for detecting single antibody-forming cells.用于检测单个抗体形成细胞的蚀斑技术的进一步改进。
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Rheumatoid factor in Nigerian sera.尼日利亚血清中的类风湿因子。
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The immunodepressive effect of a murine plasmodium and its interaction with murine oncogenic viruses.一种鼠疟原虫的免疫抑制作用及其与鼠致癌病毒的相互作用。
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Heterophilic antibodies in relation to malarial infection: population and experimental studies.与疟疾感染相关的嗜异性抗体：人群及实验研究
Clin Exp Immunol. 1974 Sep;18(1):89-93.
8
Possible role of a B-cell mitogen in hypergammaglobulinaemia in malaria and trypanosomiasis.B细胞有丝分裂原在疟疾和锥虫病高丙种球蛋白血症中的可能作用。
Lancet. 1974 Mar 16;1(7855):435-6. doi: 10.1016/s0140-6736(74)92386-1.
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Immunosuppression in murine malaria. II. The effect on reticulo-endothelial and germinal centre function.鼠疟中的免疫抑制。II. 对网状内皮系统和生发中心功能的影响。
Clin Exp Immunol. 1971 Sep;9(3):345-54.
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Immunosuppression in murine malaria. I. General characteristics.小鼠疟疾中的免疫抑制。I. 一般特征。
Clin Exp Immunol. 1971 Mar;8(3):467-78.

啮齿动物疟疾感染期间的多克隆B细胞激活。

Polyclonal B-cell activation during rodent malarial infections.

作者信息

Freeman R R, Parish C R

出版信息

Clin Exp Immunol. 1978 Apr;32(1):41-5.

PMID:352584
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1541288/
Abstract

The numbers of 'background' plaque-forming cells (PFC) secreting IgM specific for either sheep erythrocytes or horse erythrocytes were found to be elevated in the spleens of BALB/c mice during Plasmodium berghei and P. yoelii infection. 'Background' PFC numbers were similarly elevated in the spleens of uninfected mice injected with high speed supernatants of lysates of parasitized red blood cells. The active factor (or factors) in the supernatants was (were) non-dialysable and stable at 56 degrees C, but was (were) destroyed by heating to 100 degrees C.

摘要

发现在感染伯氏疟原虫和约氏疟原虫期间，BALB/c小鼠脾脏中分泌针对绵羊红细胞或马红细胞的IgM的“背景”噬斑形成细胞（PFC）数量增加。在注射了寄生红细胞裂解物高速上清液的未感染小鼠脾脏中，“背景”PFC数量同样增加。上清液中的活性因子不可透析，在56℃下稳定，但加热至100℃会被破坏。