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多模态研究探讨直肠癌手术后长期的肠、尿和性功能。

A multi-modal study examining long-term bowel, urinary, and sexual function after rectal cancer surgery.

机构信息

Department of Surgery, University of Michigan, 1500 E Medical Center Dr., Ann Arbor, MI, 48109, USA; Center for Healthcare Outcomes and Policy, University of Michigan, 2800 Plymouth Road, North Campus Research Complex, Bldg. 16, Ann Arbor, MI, 48109, USA.

Department of Surgery, University of Michigan, 1500 E Medical Center Dr., Ann Arbor, MI, 48109, USA.

出版信息

Am J Surg. 2022 Jul;224(1 Pt B):562-568. doi: 10.1016/j.amjsurg.2022.02.046. Epub 2022 Mar 3.

Abstract

BACKGROUND

Many rectal cancer survivors experience persistent bowel, urinary, and sexual dysfunction. A better understanding of their lived experience can help guide survivorship care.

METHODS

Multi-modal study of patients who underwent rectal cancer surgery from 2015 to 2019 at a single institution. Surveys and qualitative interviews were used to describe patients' postoperative symptom burden and its impact on their quality of life.

RESULTS

The total number of survey respondents was 188 (response rate = 63.5%). Among participants, 41.5% reported their bowel habits, bladder habits (7.8%) and sexual function (36.2%) to be a "moderate" or "big problem" in the past four weeks. The lived experiences varied widely even among patients who report similar symptom burden.

CONCLUSIONS

Rectal cancer survivors commonly face lasting symptoms that negatively impact their quality of life for years after surgery. Additional support extending beyond the perioperative period is needed for patients with persistent dysfunction.

摘要

背景

许多直肠癌幸存者会持续出现肠道、泌尿和性功能障碍。深入了解他们的生活体验可以帮助指导生存者护理。

方法

对 2015 年至 2019 年在一家机构接受直肠癌手术的患者进行多模式研究。使用调查和定性访谈来描述患者术后的症状负担及其对生活质量的影响。

结果

总共调查了 188 名受访者(回应率为 63.5%)。在参与者中,41.5%的人报告在过去四周内,他们的肠道习惯、膀胱习惯(7.8%)和性功能(36.2%)存在“中度”或“大问题”。即使是报告相似症状负担的患者,其生活体验也存在很大差异。

结论

直肠癌幸存者在手术后多年常常面临持续的症状,这些症状对他们的生活质量产生负面影响。对于持续存在功能障碍的患者,需要在围手术期之外提供额外的支持。

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