Deane Colleen S, da Silveira Willian A, Herranz Raúl
Department of Sport and Health Science, College of Life and Environmental Sciences, University of Exeter, Exeter EX1 2LU, UK.
Living Systems Institute, University of Exeter, Stocker Road, Exeter EX4 4QD, UK.
iScience. 2022 Feb 15;25(3):103920. doi: 10.1016/j.isci.2022.103920. eCollection 2022 Mar 18.
The European research community, via European Space Agency (ESA) spaceflight opportunities, has significantly contributed toward our current understanding of spaceflight biology. Recent molecular biology experiments include "omic" analysis, which provides a holistic and systems level understanding of the mechanisms underlying phenotypic adaptation. Despite vast interest in, and the immense quantity of biological information gained from space omics research, the knowledge of ESA-related space omics works as a collective remains poorly defined due to the recent exponential application of omics approaches in space and the limited search capabilities of pre-existing records. Thus, a review of such contributions is necessary to clarify and promote the development of space omics among ESA and ESA state members. To address this gap, in this review, we i) identified and summarized omics works led by European researchers, ii) geographically described these omics works, and iii) highlighted potential caveats in complex funding scenarios among ESA member states.
欧洲研究界通过欧洲航天局（ESA）的太空飞行机会，为我们当前对太空飞行生物学的理解做出了重大贡献。最近的分子生物学实验包括“组学”分析，它能从整体和系统层面理解表型适应背后的机制。尽管人们对太空组学研究兴趣浓厚，且从中获得了大量生物信息，但由于组学方法最近在太空中的指数级应用以及现有记录搜索能力有限，作为一个整体的与ESA相关的太空组学工作的知识仍定义不明确。因此，有必要对这些贡献进行综述，以阐明并促进ESA及其成员国之间太空组学的发展。为填补这一空白，在本综述中，我们：i）确定并总结了欧洲研究人员主导的组学工作；ii）按地理位置描述了这些组学工作；iii）强调了ESA成员国复杂资助情况下的潜在注意事项。
