Mineoka Yusuke, Ishii Michiyo, Hashimoto Yoshitaka, Yamashita Aki, Takemura Takahiro, Yamaguchi Sachiyo, Toyoda Machiko, Fukui Michiaki
Department of Internal Medicine, Otsu City Hospital, Otsu 520-0804, Japan.
Department of Endocrinology and Metabolism, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto 602-8566, Japan.
J Clin Med. 2022 Feb 27;11(5):1314. doi: 10.3390/jcm11051314.
Malnutrition and diabetes are likely to co-occur. There are few reports on the association between nutritional status and foot risk in patients with type 2 diabetes (T2D). Therefore, we aimed to investigate this relationship in this cross-sectional study. We investigated the relationships between objective data assessment (ODA), especially Controlling Nutritional Status (CONUT) score and foot risk, evaluated by the International Working Group on the Diabetic Foot (IWGDF), in consecutive patients with T2D. Patients were divided into groups 0 to 3 by IWGDF, and groups 1 to 3 were defined as high-risk groups. Among 469 patients, 42.6% (n = 200) of them had high-risk foot. Patients with high-risk foot were significantly older (71.2 ± 11.3 vs. 64.2 ± 13.4 years, p < 0.001) and had a longer duration of diabetes (18.0 ± 12.0 vs. 11.5 ± 10.0 years, p < 0.001) than those in the low-risk group. In the high-risk group, serum albumin level, total lymphocyte count, hemoglobin, and CONUT score were significantly worse, especially in older patients (≥75 years). Multivariate logistic regression analysis showed that there was a positive correlation between CONUT score and high-risk foot in older patients (OR, 1.37; 95% CI, 1.05−1.86; p = 0.021). Our results indicated that nutritional status, assessed by ODA, correlated with high-risk foot, especially in older patients with T2D.
营养不良和糖尿病可能同时出现。关于2型糖尿病(T2D)患者营养状况与足部风险之间的关联,相关报道较少。因此,我们旨在通过这项横断面研究来调查这种关系。我们在连续的T2D患者中,研究了客观数据评估(ODA),尤其是控制营养状况(CONUT)评分与糖尿病足国际工作组(IWGDF)评估的足部风险之间的关系。根据IWGDF将患者分为0至3组,其中1至3组被定义为高危组。在469例患者中,42.6%(n = 200)有足部高危风险。足部高危风险患者比低风险组患者年龄显著更大(71.2 ± 11.3岁 vs. 64.2 ± 13.4岁,p < 0.001),糖尿病病程更长(18.0 ± 12.0年 vs. 11.5 ± 10.0年,p < 0.001)。在高危组中,血清白蛋白水平、总淋巴细胞计数、血红蛋白和CONUT评分显著更差,尤其是在老年患者(≥75岁)中。多因素逻辑回归分析显示,老年患者的CONUT评分与足部高危风险呈正相关(OR,1.37;95%CI,1.05−1.86;p = 0.021)。我们的结果表明,通过ODA评估的营养状况与足部高危风险相关,尤其是在老年T2D患者中。