Departamento de Medicina y Cirugía, Facultad Ciencias de la Salud, Universidad Cardenal Herrera-CEU, CEU Universities, 46115 Valencia, Spain.
Int J Environ Res Public Health. 2022 Feb 22;19(5):2499. doi: 10.3390/ijerph19052499.
The complex interaction between cardiac and renal functions is known. However, when these functions are disrupted, many intricate and sensitive interactions between these organs are failed by several pathophysiological ways. As a result, this malfunction is clinically evident by sign and symptoms associated to intravascular and interstitial congestion. In this sense, the adverse impact of venous congestion on renal function has long been recognized. Currently, the presence of a specific subtype of nephropathy associated to congestion has been suggested. Even though no diagnosis criteria has been clearly stablished, and no renal specific histological pattern were reported; studies regarding this issue may help to improve the handling and therapeutic principles in affected patients.
心脏和肾功能之间的复杂相互作用是已知的。然而,当这些功能受到干扰时,这些器官之间的许多复杂而敏感的相互作用会通过几种病理生理途径失效。结果,这种功能障碍通过与血管内和间质充血相关的体征和症状在临床上表现明显。从这个意义上说,静脉充血对肾功能的不良影响早已被认识到。目前,已经提出了一种与充血相关的特定类型的肾病。尽管尚未明确建立诊断标准,也没有报告肾脏的特定组织学模式;但关于这个问题的研究可能有助于改善受影响患者的处理和治疗原则。