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Hemopoietic stem cells "age" structure revealed by the exogenous colony forming method.

作者信息

Gaidul K V, Tsyrlova I G, Kozlov V A

出版信息

Biomed Pharmacother. 1986;40(3):114-5.

PMID:3527289
Abstract

The number of colony forming units in mice following the transplantation of cells of bone marrow, spleen and embryonal liver, forming exogenous spleen colonies on 5, 8 and 11 days has been determined. It has been shown that stem cell subpopulation forming colonies on 5 day (CFUs-5) was notable for lower capacity for self maintenance, and contained predominantly by erythroid colonies, these CFUs-5 were mainly in embryonal liver and less in reduced in the hemopoietic populations in mice.

摘要

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