炎症性树突状细胞上同时存在朗格汉斯细胞和交错突细胞抗原标志物。
The simultaneous presence of Langerhans' cell and interdigitating cell antigenic markers on inflammatory dendritic cells.
作者信息
Alegre V A, MacDonald D M, Poulter L W
出版信息
Clin Exp Immunol. 1986 May;64(2):330-3.
Abstract
Immunohistological studies have been performed on tissues from various dermatological conditions using two monoclonal antibodies, RFD1 and NA1/34. These reagents were used to determine whether antigen expression restricted to interdigitating cells (RFD1+) and Langerhans' cells (NA1/34+) in normal tissues might occur together on dendritic cells involved in cutaneous inflammatory reactions. The results presented demonstrate that in psoriasis, allergic contact dermatitis and atopic dermatitis a proportion of the inflammatory dendritic cells express both antigens.
摘要
已使用两种单克隆抗体RFD1和NA1/34对各种皮肤病状况的组织进行了免疫组织学研究。这些试剂用于确定正常组织中局限于指状突细胞（RFD1+）和朗格汉斯细胞（NA1/34+）的抗原表达是否可能在参与皮肤炎症反应的树突状细胞上同时出现。所呈现的结果表明，在银屑病、过敏性接触性皮炎和特应性皮炎中，一部分炎性树突状细胞同时表达这两种抗原。
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