Li Jianfang, Guo Xiaofang, Li Yanhan, Hu Ningzhu, Sun Jing, Wu Meini, Zhou Hongning, Hu Yunzhang
Institute of Medical Biology, Chinese Academy of Medical Sciences and Peking Union Medical college, Kunming, 650118, China.
Yunnan Key Laboratory of Vaccine Research and Development of Severe Infection Disease, Kunming, 650118, China.
Arch Virol. 2022 Apr;167(4):1221-1223. doi: 10.1007/s00705-022-05403-z. Epub 2022 Mar 12.
Banna virus (BAV) is a typical arbovirus whose infection is associated with fever and viral encephalitis. The whole genome of BAV is composed of 12 RNA segments. BAVs, which have been divided into three genotypes (A, B, and C) based on phylogenetic analysis of segment 12 or segment 9, are currently undergoing rapid evolution. Recent studies have shown that BAV variation can exceed intraspecific limits and generate novel viruses. In the current study, a new BAV strain, named 113c5, was isolated from Culex tritaeniorhynchus and found to be a member of genotype A2 based on phylogenetic analysis of segments 9 and 12. The complete genome sequence of the new BAV strain described in the current study might contribute to the surveillance of evolutionary characteristics of BAVs.
版纳病毒（BAV）是一种典型的虫媒病毒，其感染与发热和病毒性脑炎有关。BAV的全基因组由12个RNA片段组成。基于第12或第9片段的系统发育分析，BAV已被分为三种基因型（A、B和C），目前正在经历快速进化。最近的研究表明，BAV变异可超过种内界限并产生新型病毒。在本研究中，从三带喙库蚊中分离出一株新的BAV毒株，命名为113c5，基于第9和12片段的系统发育分析，发现它是A2基因型的成员。本研究中描述的新BAV毒株的完整基因组序列可能有助于对BAV进化特征的监测。
