Al-Taee Riad, Al-Saedi Aqeel Ibrahim Lazim, Nahidh Mohammed
Department of Oral and Maxillofacial Surgery, College of Dentistry, Almaaqal University, Basrah, Iraq.
Department of Oral Diagnosis, College of Dentistry, University of Basrah, Basrah, Iraq.
J Orthod Sci. 2022 Jan 28;11:4. doi: 10.4103/jos.jos_148_21. eCollection 2022.
Thalassemia, one of the most widespread autosomal recessive disorders, is characterized by anomalies in the synthesis of hemoglobin beta chains and is frequently coupled with variable craniofacial characteristics. Thalassemic patients suffer from severe anemia, which triggers several defense mechanisms in the body, such as bone marrow expansion, which forces the bones to expand, resulting in craniofacial bone deformities. This study aims to assess and compare the orofacial dimensions of β-thalassemia patients with those of a control group across similar ages and gender.
Three hundred Iraqi individuals agreed to participate in this study (150 non-thalassemic and 150 thalassemic patients with an equal distribution of genders). A well-trained researcher carried out five anthropometric measurements by using an electronic digital caliper. Gender and group differences were tested using an independent sample t test.
Mouth width showed clinical and statistically significant group differences among all measurements in the study group.
All measurements except mouth width showed nonsignificant clinical group differences.
地中海贫血是最常见的常染色体隐性疾病之一，其特征是血红蛋白β链合成异常，并常常伴有各种颅面特征变化。地中海贫血患者患有严重贫血，这会引发身体的多种防御机制，如骨髓扩张，迫使骨骼扩张，导致颅面骨畸形。本研究旨在评估和比较β地中海贫血患者与同龄、同性别的对照组的口腔颌面部尺寸。
300名伊拉克人同意参与本研究（150名非地中海贫血患者和150名地中海贫血患者，性别分布均等）。一名训练有素的研究人员使用电子数字卡尺进行了五项人体测量。使用独立样本t检验对性别和组间差异进行了测试。
在研究组的所有测量中，口宽显示出临床和统计学上的显著组间差异。
除口宽外，所有测量均显示出无显著临床组间差异。
