Stinson Lisa F, Geddes Donna T
School of Molecular Sciences, The University of Western Australia, Perth, Australia.
School of Molecular Sciences, The University of Western Australia, Perth, Australia.
Trends Microbiol. 2022 May;30(5):408-410. doi: 10.1016/j.tim.2022.02.007. Epub 2022 Mar 10.
Microbial metabolites mediate the impact of the microbiome on host physiology. Here, we highlight metabolites of interest for early-life programming and synthesise early evidence that maternally derived microbial metabolites are transmitted to the infant via human milk. We advocate for the use of targeted and untargeted metabolomics to compliment current milk microbiome work.
微生物代谢产物介导微生物群对宿主生理的影响。在此，我们重点介绍对生命早期编程有重要意义的代谢产物，并综合早期证据表明，母体来源的微生物代谢产物通过母乳传递给婴儿。我们提倡使用靶向和非靶向代谢组学来补充当前关于母乳微生物群的研究工作。
