• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

表现为快速进展的肢端结节性黑色素瘤。

Acral Nodular Melanoma Presenting With Rapid Progression.

作者信息

Jagtap Sunil Vitthalrao, Khoja Shoaib, Billawaria Sonam, Chou Teh Shin Richard, Jagtap Swati Sunil

机构信息

Department of Pathology, Surgery, Physiology, Krishna Institute of Medical Sciences Karad, Maharashtra, India.

出版信息

J Cutan Aesthet Surg. 2021 Oct-Dec;14(4):426-432. doi: 10.4103/JCAS.JCAS_183_20.

DOI:10.4103/JCAS.JCAS_183_20
PMID:35283606
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8906262/
Abstract

Melanoma is a malignant tumor that is derived from melanocytes of the skin and other sites. Melanoma accounts for 1% to 3% of all malignancies and 1% to 2% of all cancer deaths worldwide. We are presenting a case of a 42-year-old female who presented to the surgery department with a growth over the right heel since 18 months, with a history of trauma to the site. The lesion showed rapid progression with a large mass and secondary skin ulceration and sloughing. A PET scan showed an enhancing lesion on the right heel measuring 11 mm in thickness. There was no evidence of any systemic organ or any lymph node metastasis. Surgical excision and reconstruction on the part of the heel by a local flap with sural graft with split-thickness skin grafting was done. The excised growth was sent for histopathology. The histopathological diagnosis of nodular melanoma (NM) of the heel was given. We are presenting this case for its clinical, histopathological, and surgical management.

摘要

黑色素瘤是一种源自皮肤及其他部位黑素细胞的恶性肿瘤。黑色素瘤占全球所有恶性肿瘤的1%至3%,占所有癌症死亡病例的1%至2%。我们报告一例42岁女性病例,该患者自18个月前起右足跟部出现肿物,有该部位外伤史。病变迅速进展,形成巨大肿块,并继发皮肤溃疡和坏死。PET扫描显示右足跟部有一强化病灶,厚度为11毫米。未发现任何全身器官或淋巴结转移的证据。通过局部皮瓣联合腓肠肌皮瓣及中厚皮片移植对足跟部进行了手术切除和重建。切除的肿物送去做组织病理学检查。组织病理学诊断为足跟部结节性黑色素瘤(NM)。我们展示该病例是为了介绍其临床、组织病理学及手术治疗情况。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e7f/8906262/88bc321fc349/JCAS-14-426-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e7f/8906262/a231ebcf0071/JCAS-14-426-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e7f/8906262/6667b0a7048b/JCAS-14-426-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e7f/8906262/e2806172c3ba/JCAS-14-426-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e7f/8906262/b5e9b22ec8a7/JCAS-14-426-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e7f/8906262/f654145949ad/JCAS-14-426-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e7f/8906262/d99e3c57e01b/JCAS-14-426-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e7f/8906262/88bc321fc349/JCAS-14-426-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e7f/8906262/a231ebcf0071/JCAS-14-426-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e7f/8906262/6667b0a7048b/JCAS-14-426-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e7f/8906262/e2806172c3ba/JCAS-14-426-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e7f/8906262/b5e9b22ec8a7/JCAS-14-426-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e7f/8906262/f654145949ad/JCAS-14-426-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e7f/8906262/d99e3c57e01b/JCAS-14-426-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e7f/8906262/88bc321fc349/JCAS-14-426-g007.jpg

相似文献

1
Acral Nodular Melanoma Presenting With Rapid Progression.表现为快速进展的肢端结节性黑色素瘤。
J Cutan Aesthet Surg. 2021 Oct-Dec;14(4):426-432. doi: 10.4103/JCAS.JCAS_183_20.
2
Malignant melanoma presenting as a nonhealing heel ulceration.表现为足跟部不愈合溃疡的恶性黑色素瘤。
J Am Podiatr Med Assoc. 2014 May;104(3):295-7. doi: 10.7547/0003-0538-104.3.295.
3
Rare nodular malignant melanoma of the heel in the Caribbean: A case report.加勒比地区足跟部罕见的结节性恶性黑色素瘤:一例报告。
Int J Surg Case Rep. 2017;30:172-176. doi: 10.1016/j.ijscr.2016.11.047. Epub 2016 Nov 27.
4
The importance of wound biopsy in the accurate diagnosis of acral malignant melanoma presenting as a foot ulcer.伤口活检在准确诊断表现为足部溃疡的肢端恶性黑色素瘤中的重要性。
Int J Low Extrem Wounds. 2013 Dec;12(4):289-92. doi: 10.1177/1534734613512505. Epub 2013 Dec 9.
5
Role of In Vivo Reflectance Confocal Microscopy in the Analysis of Melanocytic Lesions.体内反射共聚焦显微镜在黑素细胞性病变分析中的作用
Acta Dermatovenerol Croat. 2018 Apr;26(1):64-67.
6
[Surgical treatment of acral melanoma: a report of eight cases].[肢端黑色素瘤的外科治疗:8例报告]
Ann Chir Plast Esthet. 2015 Feb;60(1):39-43. doi: 10.1016/j.anplas.2013.05.002. Epub 2013 Jun 29.
7
Acral malignant melanoma and striated palmoplantar keratoderma (Brunauer-Fohs-Siemens syndrome): a fortuitous association?肢端恶性黑色素瘤与掌跖纹状角化病(布鲁瑙尔-福斯-西门子综合征):一种偶然的关联?
Dermatol Surg. 2004 Dec;30(12 Pt 2):1539-42. doi: 10.1111/j.1524-4725.2004.30564.x.
8
Acral lentiginous melanoma: a case control study and guidelines update.肢端雀斑样痣黑色素瘤:一项病例对照研究及指南更新
Case Rep Med. 2011;2011:670581. doi: 10.1155/2011/670581. Epub 2011 Apr 6.
9
Giant malignant melanoma: a case report.巨大恶性黑色素瘤:一例报告。
Acta Chir Plast. 2012;54(2):59-61.
10
Tattoo Pigment within Regional Lymph Nodes Mimicking Cutaneous Melanoma Metastasis.淋巴结内的纹身颜料,类似皮肤黑色素瘤转移。
Acta Dermatovenerol Croat. 2020 Jul;28(1):47-48.

引用本文的文献

1
A Rare Disease Presentation of Malignant Fungating Acral Melanoma of the Hand.手部恶性溃疡性肢端黑色素瘤的罕见病例报告
J Hand Surg Glob Online. 2023 Feb 25;5(3):386-390. doi: 10.1016/j.jhsg.2023.01.015. eCollection 2023 May.

本文引用的文献

1
Prognostic factors in patients with localized primary cutaneous melanoma.局限性原发性皮肤黑色素瘤患者的预后因素
Acta Dermatovenerol Alp Pannonica Adriat. 2012;21(2):27-31.
2
Melanoma of the hand and foot: epidemiological, prognostic and genetic features. A systematic review.手足部黑素瘤:流行病学、预后和遗传学特征。系统综述。
Br J Dermatol. 2012 Apr;166(4):727-39. doi: 10.1111/j.1365-2133.2011.10772.x.
3
Superficial spreading and nodular melanoma are distinct biological entities: a challenge to the linear progression model.
浅表扩散型和结节型黑色素瘤是两种截然不同的生物学实体:对线性进展模型的挑战。
Melanoma Res. 2012 Feb;22(1):1-8. doi: 10.1097/CMR.0b013e32834e6aa0.
4
Immunohistochemical characteristics of melanoma.黑色素瘤的免疫组织化学特征
J Cutan Pathol. 2008 May;35(5):433-44. doi: 10.1111/j.1600-0560.2007.00891.x.
5
Evidence and interdisciplinary consense-based German guidelines: diagnosis and surveillance of melanoma.基于证据和多学科共识的德国黑色素瘤诊疗指南:黑色素瘤的诊断与监测
Melanoma Res. 2007 Dec;17(6):393-9. doi: 10.1097/CMR.0b013e3282f05039.
6
Diagnosis and treatment of malignant melanoma of the foot.足部恶性黑色素瘤的诊断与治疗
Foot Ankle Int. 2006 Sep;27(9):696-705. doi: 10.1177/107110070602700908.
7
Histologic criteria for diagnosing primary cutaneous malignant melanoma.
Mod Pathol. 2006 Feb;19 Suppl 2:S34-40. doi: 10.1038/modpathol.3800508.
8
Survival of patients with primary pedal melanoma.
J Foot Ankle Surg. 2003 Jul-Aug;42(4):193-8. doi: 10.1016/s1067-2516(03)70028-3.