Yi Zhiran, Liu Zhaoxu, Li Wenbo, Ruan Tao, Chen Xiang, Liu Jingquan, Yang Bin, Zhang Wenming
State Key Laboratory of Mechanical System and Vibration, School of Mechanical Engineering, Shanghai Jiao Tong University, Shanghai, 200240, China.
National Key Laboratory of Science and Technology on Micro/Nano Fabrication, Department of Micro/Nano Electronics, Shanghai Jiao Tong University, Shanghai, 200240, China.
Adv Mater. 2022 Apr;34(16):e2110291. doi: 10.1002/adma.202110291. Epub 2022 Mar 14.
Piezoelectric arterial pulse wave dynamics are traditionally considered to be similar to those of typical blood pressure waves. However, achieving accurate continuous blood pressure wave monitoring based on arterial pulse waves remains challenging, because the correlation between piezoelectric pulse waves and their related blood pressure waves is unclear. To address this, the correlation between piezoelectric pulse waves and blood pressure waves is first elucidated via theoretical, simulation, and experimental analysis of these dynamics. Based on this correlation, the authors develop a wireless wearable continuous blood pressure monitoring system, with better portability than conventional systems that are based on the pulse wave velocity between multiple sensors. They explore the feasibility of achieving wearable continuous blood pressure monitoring without motion artifacts, using a single piezoelectric sensor. These findings eliminate the controversy over the arterial pulse wave piezoelectric response, and can potentially be used to develop a portable wearable continuous blood pressure monitoring device for the early prevention and daily control of hypertension.
传统上认为压电动脉脉搏波动力学与典型血压波的动力学相似。然而，基于动脉脉搏波实现准确的连续血压波监测仍然具有挑战性，因为压电脉搏波与其相关血压波之间的相关性尚不清楚。为了解决这一问题，首先通过对这些动力学进行理论、模拟和实验分析，阐明了压电脉搏波与血压波之间的相关性。基于这种相关性，作者开发了一种无线可穿戴连续血压监测系统，其便携性优于基于多个传感器之间脉搏波速度的传统系统。他们探索了使用单个压电传感器实现无运动伪影的可穿戴连续血压监测的可行性。这些发现消除了关于动脉脉搏波压电响应的争议，并有可能用于开发一种便携式可穿戴连续血压监测设备，用于高血压的早期预防和日常控制。
