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Deep proteome profiling promotes whole proteome characterization and drug discovery for esophageal squamous cell carcinoma.

作者信息

Liu Wei, Cui Yongping, Liu Wen, Liu Zhihua, Xu Liyan, Li Enmin

机构信息

College of Science, Heilongjiang Institute of Technology, Harbin 150050, China.

Guangdong Provincial Key Laboratory of Infectious Diseases and Molecular Immunopathology, the Key Laboratory of Molecular Biology for High Cancer Incidence Coastal Chaoshan Area, Shantou University Medical College, Shantou 515041, China.

出版信息

Cancer Biol Med. 2022 Mar 14;19(3):273-7. doi: 10.20892/j.issn.2095-3941.2022.0024.

DOI:10.20892/j.issn.2095-3941.2022.0024
PMID:35289157
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8958891/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f21d/8958891/6973fe2713a1/cbm-19-273-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f21d/8958891/6973fe2713a1/cbm-19-273-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f21d/8958891/6973fe2713a1/cbm-19-273-g001.jpg

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本文引用的文献

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Phosphoproteomics reveals therapeutic targets of esophageal squamous cell carcinoma.磷酸化蛋白质组学揭示食管鳞状细胞癌的治疗靶点。
Signal Transduct Target Ther. 2021 Nov 12;6(1):381. doi: 10.1038/s41392-021-00682-5.
2
Mutational signatures in esophageal squamous cell carcinoma from eight countries with varying incidence.来自八个发病率不同国家的食管鳞癌中的突变特征。
Nat Genet. 2021 Nov;53(11):1553-1563. doi: 10.1038/s41588-021-00928-6. Epub 2021 Oct 18.
3
A multi-omics study delineates new molecular features and therapeutic targets for esophageal squamous cell carcinoma.
多组学研究描绘了食管鳞癌的新分子特征和治疗靶点。
Clin Transl Med. 2021 Sep;11(9):e538. doi: 10.1002/ctm2.538.
4
Large-scale and high-resolution mass spectrometry-based proteomics profiling defines molecular subtypes of esophageal cancer for therapeutic targeting.基于大规模和高分辨率质谱的蛋白质组学分析为治疗靶点定义了食管癌的分子亚型。
Nat Commun. 2021 Aug 16;12(1):4961. doi: 10.1038/s41467-021-25202-5.
5
Integrin-Linked Kinase Is Involved In the Proliferation and Invasion of Esophageal Squamous Cell Carcinoma.整合素连接激酶参与食管鳞状细胞癌的增殖和侵袭
J Cancer. 2020 Jan 1;11(2):324-333. doi: 10.7150/jca.33737. eCollection 2020.
6
Identification of prothymosin alpha (PTMA) as a biomarker for esophageal squamous cell carcinoma (ESCC) by label-free quantitative proteomics and Quantitative Dot Blot (QDB).通过无标记定量蛋白质组学和定量点杂交(QDB)鉴定原胸腺素α(PTMA)作为食管鳞状细胞癌(ESCC)的生物标志物。
Clin Proteomics. 2019 Apr 5;16:12. doi: 10.1186/s12014-019-9232-6. eCollection 2019.
7
Clinical potential of mass spectrometry-based proteogenomics.基于质谱的蛋白质基因组学的临床潜力。
Nat Rev Clin Oncol. 2019 Apr;16(4):256-268. doi: 10.1038/s41571-018-0135-7.
8
iTRAQ-Based Quantitative Proteomic Analyses of High Grade Esophageal Squamous Intraepithelial Neoplasia.基于iTRAQ的高级别食管鳞状上皮内瘤变定量蛋白质组学分析
Proteomics Clin Appl. 2017 Dec;11(11-12). doi: 10.1002/prca.201600167. Epub 2017 Sep 25.
9
Colorectal Cancer Cell Line Proteomes Are Representative of Primary Tumors and Predict Drug Sensitivity.结直肠癌细胞系蛋白质组可代表原发性肿瘤并预测药物敏感性。
Gastroenterology. 2017 Oct;153(4):1082-1095. doi: 10.1053/j.gastro.2017.06.008. Epub 2017 Jun 16.
10
iTRAQ-based quantitative proteomic analysis of esophageal squamous cell carcinoma.基于iTRAQ的食管鳞状细胞癌定量蛋白质组学分析
Tumour Biol. 2016 Feb;37(2):1909-18. doi: 10.1007/s13277-015-3840-1. Epub 2015 Sep 2.