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A组链球菌细胞壁对巨噬细胞吞噬活性的抑制作用。

Inhibition of macrophage phagocytic activity by group A streptococcal cell walls.

作者信息

Smialowicz R J, Schwab J H

出版信息

Infect Immun. 1978 Apr;20(1):258-61. doi: 10.1128/iai.20.1.258-261.1978.

DOI:10.1128/iai.20.1.258-261.1978
PMID:352930
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC421580/
Abstract

Group A streptococcal cell walls inhibited phagocytosis of polystyrene latex particles by rat peritoneal macrophages in vitro. This inhibition was not accompanied by a measurable loss of cell viability. Group D streptococcal cell walls were relatively ineffective in altering phagocytosis. The effectiveness of group A variant streptococcal cell walls and peptidoglycan derived from group A cell walls was increased if cell wall preparations were added to macrophage cultures 12 h before, rather than simultaneously with, latex particles.

摘要

A组链球菌细胞壁在体外可抑制大鼠腹膜巨噬细胞对聚苯乙烯乳胶颗粒的吞噬作用。这种抑制作用并未伴随着细胞活力的可测量损失。D组链球菌细胞壁在改变吞噬作用方面相对无效。如果在巨噬细胞培养物中,在加入乳胶颗粒前12小时而非同时加入细胞壁制剂,则A组变异链球菌细胞壁和源自A组细胞壁的肽聚糖的效力会增强。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/717f/421580/4a5903545eb8/iai00196-0269-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/717f/421580/4a5903545eb8/iai00196-0269-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/717f/421580/4a5903545eb8/iai00196-0269-a.jpg

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Inhibition of macrophage phagocytic activity by group A streptococcal cell walls.A组链球菌细胞壁对巨噬细胞吞噬活性的抑制作用。
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引用本文的文献

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Stimulation of migration of human monocytes by bacterial cell walls and muramyl peptides.细菌细胞壁和胞壁酰肽对人单核细胞迁移的刺激作用。
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Group A streptococcal peptidoglycan-polysaccharide inhibits phagocytic activity of human polymorphonuclear leukocytes.A组链球菌肽聚糖-多糖抑制人多形核白细胞的吞噬活性。
Infect Immun. 1984 Aug;45(2):378-83. doi: 10.1128/iai.45.2.378-383.1984.
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Interaction of group A streptococcal peptidoglycan polysaccharide with human polymorphonuclear leukocytes: implications for pathogenesis of chronic inflammation.

本文引用的文献

1
Effects of streptococcal cell wall fragments on phagocytosis and tissue culture cells.链球菌细胞壁片段对吞噬作用和组织培养细胞的影响。
Infect Immun. 1970 Mar;1(3):232-42. doi: 10.1128/iai.1.3.232-242.1970.
2
Technique for differentiating particles that are cell-associated or ingested by macrophages.区分与细胞相关或被巨噬细胞摄取的颗粒的技术。
Appl Microbiol. 1973 Mar;25(3):471-5. doi: 10.1128/am.25.3.471-475.1973.
3
Cytotoxicity of rat macrophages activated by persistent or biodegradable bacterial cell walls.
A组链球菌肽聚糖多糖与人多形核白细胞的相互作用:对慢性炎症发病机制的影响。
Infect Immun. 1984 Jul;45(1):160-5. doi: 10.1128/iai.45.1.160-165.1984.
Infect Immun. 1977 Sep;17(3):599-606. doi: 10.1128/iai.17.3.599-606.1977.
4
Processing of streptococcal cell walls by rat macrophages and human monocytes in vitro.
Infect Immun. 1977 Sep;17(3):591-8. doi: 10.1128/iai.17.3.591-598.1977.
5
Decreased phagocytosis by peritoneal macrophages from BCG-treated mice: induction of the phagocytic defect in normal macrophages with BCG in vitro.卡介苗处理的小鼠腹膜巨噬细胞吞噬作用降低:体外使用卡介苗诱导正常巨噬细胞出现吞噬缺陷。
Cell Immunol. 1977 Mar 15;29(2):295-311. doi: 10.1016/0008-8749(77)90324-0.