Rezapour Mehdi, Abbasi Mohammad
Department of Chemistry, Faculty of Science, Persian Gulf University, 75169, Bushehr, Iran.
Mol Divers. 2023 Feb;27(1):159-165. doi: 10.1007/s11030-022-10403-x. Epub 2022 Mar 16.
The reaction of dibenzyl disulfide with various bromine complexes as oxidants and DMSO as solvent can produce thioamides in high yield at 110 °C. Tertiary amines like pyridine and quinoline, which were utilized in this catalyst, are known to generate bromine-addition complexes. The approach is metal- and additive-free, making it a simple and cost-effective way to make a variety of thioamides under favorable circumstances.
二苄基二硫化物与各种溴配合物作为氧化剂、二甲基亚砜作为溶剂反应，在110°C下可高产率地生成硫代酰胺。该催化剂中使用的吡啶和喹啉等叔胺已知可生成溴加成配合物。该方法无需金属和添加剂，在有利条件下是制备各种硫代酰胺的一种简单且经济高效的方法。
