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新型气单胞菌噬菌体 AHP-1 的全基因组序列分析与系统进化分类，该噬菌体可能属于四瘤病毒属。

Complete genome sequence analysis and phylogenetic classification of the novel Aeromonas phage AHP-1, a potential member of the genus Tequatrovirus.

机构信息

College of Veterinary Medicine and Research Institute of Veterinary Medicine, Chungnam National University, Yuseong-gu, Daejeon, 34134, Republic of Korea.

Department of Marine Life Sciences, Jeju National University, Jeju, Jeju Self-Governing Province, 63243, Republic of Korea.

出版信息

Arch Virol. 2022 Apr;167(4):1225-1230. doi: 10.1007/s00705-022-05418-6. Epub 2022 Mar 16.

DOI:10.1007/s00705-022-05418-6
PMID:35296935
Abstract

Aeromonas phage AHP-1 was originally isolated from crucian carp (Carassius carassius) tissue. It was able to infect Aeromonas hydrophila and A. salmonicida. Genome sequence analysis revealed a 218,317-bp-long linear genome with an overall G + C content of 47.9%, 315 open reading frames (ORFs), and 25 tRNA sequences. Its genome was found to contain 67 unique ORFs (21.26%) that did not show any homology to previously characterized proteins. A comparative genome analysis suggested that its closest neighbors are unclassified phages belonging to the genus Tequatrovirus of the subfamily Tevenvirinae.

摘要

气单胞菌噬菌体 AHP-1 最初从鲫鱼（Carassius carassius）组织中分离得到。它能够感染嗜水气单胞菌和鲑气单胞菌。基因组序列分析显示，该噬菌体具有一条 218317bp 的线性基因组，总 GC 含量为 47.9%，包含 315 个开放阅读框（ORFs）和 25 个 tRNA 序列。该噬菌体基因组中包含 67 个独特的 ORFs（21.26%），这些 ORFs 与之前鉴定的蛋白均没有同源性。比较基因组分析表明，其最接近的亲缘关系是属于 Tevenvirinae 亚科的未分类噬菌体 Tequatrovirus 属。

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