Department of Psychosomatic Medicine and Psychotherapy, Medical University Hospital Tübingen, Tübingen, Germany.
Center of Excellence for Eating Disorders (KOMET), Tübingen, Germany.
Nat Rev Dis Primers. 2022 Mar 17;8(1):16. doi: 10.1038/s41572-022-00344-y.
Binge eating disorder (BED) is characterized by regular binge eating episodes during which individuals ingest comparably large amounts of food and experience loss of control over their eating behaviour. The worldwide prevalence of BED for the years 2018-2020 is estimated to be 0.6-1.8% in adult women and 0.3-0.7% in adult men. BED is commonly associated with obesity and with somatic and mental health comorbidities. People with BED experience considerable burden and impairments in quality of life, and, at the same time, BED often goes undetected and untreated. The aetiology of BED is complex, including genetic and environmental factors as well as neuroendocrinological and neurobiological contributions. Neurobiological findings highlight impairments in reward processing, inhibitory control and emotion regulation in people with BED, and these neurobiological domains are targets for emerging treatment approaches. Psychotherapy is the first-line treatment for BED. Recognition and research on BED has increased since its inclusion into DSM-5; however, continuing efforts are needed to understand underlying mechanisms of BED and to improve prevention and treatment outcomes for this disorder. These efforts should also include screening, identification and implementation of evidence-based interventions in routine clinical practice settings such as primary care and mental health outpatient clinics.
暴食障碍(BED)的特征是定期出现暴食发作,在此期间个体摄入大量食物,并表现出对进食行为失去控制。2018-2020 年全球成年女性暴食障碍的患病率估计为 0.6-1.8%,成年男性为 0.3-0.7%。暴食障碍通常与肥胖以及躯体和心理健康共病有关。暴食障碍患者经历着相当大的负担和生活质量受损,同时,暴食障碍往往未被发现和治疗。暴食障碍的病因复杂,包括遗传和环境因素以及神经内分泌和神经生物学因素。神经生物学研究结果强调了暴食障碍患者在奖励处理、抑制控制和情绪调节方面的缺陷,这些神经生物学领域是新兴治疗方法的目标。心理治疗是暴食障碍的一线治疗方法。自从暴食障碍被纳入 DSM-5 以来,对其的认识和研究有所增加;然而,仍需要继续努力,以了解暴食障碍的潜在机制,并改善该障碍的预防和治疗效果。这些努力还应包括在初级保健和心理健康门诊等常规临床实践环境中进行筛查、识别和实施基于证据的干预措施。