Department of Psychiatry, Bellvitge University Hospital-IDIBELL, 08907 L'Hospitalet de Llobregat, Spain.
Psychiatry and Mental Health Group, Neuroscience Program, Institut d'Investigació Biomèdica de Bellvitge-IDIBELL, 08907 L'Hospitalet de Llobregat, Spain.
Nutrients. 2021 Jun 23;13(7):2145. doi: 10.3390/nu13072145.
Eating disorders (EDs) are severe psychiatric illnesses that require individualized treatments. Decision-making deficits have been associated with EDs. Decision-making learning deficits denote a lack of strategies to elaborate better decisions that can have an impact on recovery and response to treatment. This study used the Iowa Gambling Task (IGT) to investigate learning differences related to treatment outcome in EDs, comparing between patients with a good and bad treatment outcome and healthy controls. Likewise, the predictive role of impaired learning performance on therapy outcome was explored. Four hundred twenty-four participants (233 ED patients and 191 healthy controls) participated in this study. Decision making was assessed using the Iowa Gambling Task before any psychological treatment. All patients received psychological therapy, and treatment outcome was evaluated at discharge. Patients with bad outcome did not show progression in the decision-making task as opposed to those with good outcome and the healthy control sample. Additionally, learning performance in the decision-making task was predictive of their future outcome. The severity of learning deficits in decision making may serve as a predictor of the treatment. These results may provide a starting point of how decision-making learning deficits are operating as dispositional and motivational factors on responsiveness to treatment in EDs.
进食障碍（EDs）是严重的精神疾病，需要个体化治疗。决策缺陷与 EDs 有关。决策学习缺陷表示缺乏制定更好决策的策略，这可能会对康复和治疗反应产生影响。本研究使用爱荷华赌博任务（IGT）来研究与 ED 治疗结果相关的学习差异，比较治疗结果良好和不良的患者与健康对照组之间的差异。同样，还探讨了学习成绩受损对治疗结果的预测作用。424 名参与者（233 名 ED 患者和 191 名健康对照组）参加了这项研究。在任何心理治疗之前，使用爱荷华赌博任务评估决策。所有患者均接受心理治疗，并在出院时评估治疗结果。与治疗结果良好的患者和健康对照组相比，治疗结果不良的患者在决策任务中没有表现出进展。此外，决策任务中的学习表现可以预测他们的未来结果。决策中学习缺陷的严重程度可能是治疗的预测指标。这些结果可能为决策学习缺陷如何作为 ED 对治疗反应的特质和动机因素提供了一个起点。
