Gridina M M, Nurislamov A R, Minina J M, Lopatkina M E, Drozdov G V, Vasilyev S A, Minaycheva L I, Belyaeva E O, Nikitina T V, Kashevarova A A, Lebedev I N, Karamysheva T V, Rubtsov N B, Serov O L
Institute of Cytology and Genetics, Siberian Branch RAS, Novosibirsk, Russia.
Institute of Cytology and Genetics, Siberian Branch RAS, Novosibirsk, Russia; Novosibirsk State University, Novosibirsk, Russia.
Stem Cell Res. 2022 May;61:102740. doi: 10.1016/j.scr.2022.102740. Epub 2022 Feb 28.
Human induced pluripotent stem cell (iPSC) line, ICGi040-A, was obtained from skin fibroblasts derived from a male patient with mosaic ring small supernumerary marker chromosome 4 (sSMS(4)) and infertility. ICGi040-A cells have karyotype 47,XY,+r(4) in 97% of cells and express a set of pluripotent markers, as well as are able to differentiate in vitro into derivatives of all three embryonic germ layers.
人诱导多能干细胞系ICGi040 - A，取自一名患有镶嵌性环状小额外标记染色体4（sSMS(4)）且不育的男性患者的皮肤成纤维细胞。ICGi040 - A细胞在97%的细胞中具有47,XY,+r(4)核型，表达一组多能性标记物，并且能够在体外分化为所有三个胚胎胚层的衍生物。
