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妊娠期糖尿病孕妇的产前抑郁:一项初步研究。

Antenatal depression among women with gestational diabetes mellitus: a pilot study.

机构信息

Department of Immunology, Bangladesh University of Health Sciences, Darus Salam Road, Dhaka, 1216, Bangladesh.

Department of Public Health, Global Communicable Disease, University of South Florida, Tampa, FL, 33620, USA.

出版信息

Reprod Health. 2022 Mar 19;19(1):71. doi: 10.1186/s12978-022-01374-1.

Abstract

BACKGROUND

Gestational diabetes mellitus (GDM) is quite prevalent in low- and middle-income countries, and has been proposed to increase the risk of depression. There is only a prior study assessing antenatal depression among the subjects with GDM in the Bangladesh, which leads this study to be investigated.

OBJECTIVE

To determine the prevalence of depressive symptoms and potential associations among pregnant women diagnosed with GDM.

METHODS

A cross-sectional study was carried out among 105 pregnant women diagnosed with GDM over the period of January to December 2017 in 4- hospitals located in two different cities (Dhaka and Barisal). A semi-structured questionnaire was developed consisting of items related to socio-demographics, reproductive health history, diabetes, anthropometrics, and depression.

RESULTS

Mild to severe antenatal depression was present in 36.2% of the subjects (i.e., 14.3%, 19% and 2.9% for mild, moderate and severe depression, respectively). None of the socio-demographic factors were associated with depression, but the history of reproductive health-related issues (i.e., abortion, neonatal death) and uncontrolled glycemic status were associated with the increased risk of depressive disorders.

CONCLUSIONS

GDM is associated with a high prevalence of depressive symptoms, which is enhanced by poor diabetes control. Thus, in women presenting with GDM, screening for depression should be pursued and treated as needed.

摘要

背景

在中低收入国家,妊娠糖尿病(GDM)相当普遍,并被认为会增加患抑郁症的风险。之前仅有一项在孟加拉国针对 GDM 患者的产前抑郁的研究,这促使我们进行了此项研究。

目的

评估 GDM 孕妇中抑郁症状的流行情况及潜在关联。

方法

本横断面研究于 2017 年 1 月至 12 月在达卡和巴里萨尔的 4 家医院,对 105 例 GDM 孕妇进行。设计了一份半结构式问卷,内容涉及社会人口统计学、生殖健康史、糖尿病、人体测量学和抑郁。

结果

36.2%的患者存在轻度至重度产前抑郁(即轻度、中度和重度抑郁的发生率分别为 14.3%、19%和 2.9%)。社会人口统计学因素均与抑郁无关,但生殖健康相关问题(如流产、新生儿死亡)和血糖控制不佳与抑郁障碍风险增加相关。

结论

GDM 与较高的抑郁症状发生率相关,且血糖控制不佳会加重这种情况。因此,对于患有 GDM 的女性,应进行抑郁筛查,并根据需要进行治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb2b/8934461/cd21c2a23440/12978_2022_1374_Fig1_HTML.jpg

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