Department of Ophthalmology, Taoyuan General Hospital, Ministry of Health and Welfare, Taoyuan, Taiwan.
Department of Ophthalmology, National Taiwan University Hospital, Taipei, Taiwan.
J Diabetes Res. 2022 Mar 9;2022:5779276. doi: 10.1155/2022/5779276. eCollection 2022.
To investigate the applicability of deep learning image assessment software VeriSee DR to different color fundus cameras for the screening of diabetic retinopathy (DR).
Color fundus images of diabetes patients taken with three different nonmydriatic fundus cameras, including 477 Topcon TRC-NW400, 459 Topcon TRC-NW8 series, and 471 Kowa nonmyd 8 series that were judged as "gradable" by one ophthalmologist were enrolled for validation. VeriSee DR was then used for the diagnosis of referable DR according to the International Clinical Diabetic Retinopathy Disease Severity Scale. Gradability, sensitivity, and specificity were calculated for each camera model.
All images (100%) from the three camera models were gradable for VeriSee DR. The sensitivity for diagnosing referable DR in the TRC-NW400, TRC-NW8, and non-myd 8 series was 89.3%, 94.6%, and 95.7%, respectively, while the specificity was 94.2%, 90.4%, and 89.3%, respectively. Neither the sensitivity nor the specificity differed significantly between these camera models and the original camera model used for VeriSee DR development ( = 0.40, = 0.065, respectively).
VeriSee DR was applicable to a variety of color fundus cameras with 100% agreement with ophthalmologists in terms of gradability and good sensitivity and specificity for the diagnosis of referable DR.
研究深度学习图像评估软件 VeriSee DR 应用于不同眼底彩色相机筛查糖尿病视网膜病变（DR）的适用性。
纳入一位眼科医生判断为“可评估”的三种不同非散瞳眼底相机（包括 477 台 Topcon TRC-NW400、459 台 Topcon TRC-NW8 系列和 471 台 Kowa 非散瞳 8 系列）拍摄的糖尿病患者眼底彩色图像，采用 VeriSee DR 根据国际临床糖尿病视网膜病变疾病严重程度量表进行可转诊 DR 的诊断。计算每个相机模型的可评估性、敏感性和特异性。
三种相机模型的所有图像（100%）均适用于 VeriSee DR。TRC-NW400、TRC-NW8 和非散瞳 8 系列诊断可转诊 DR 的敏感性分别为 89.3%、94.6%和 95.7%，特异性分别为 94.2%、90.4%和 89.3%。这些相机模型与用于开发 VeriSee DR 的原始相机模型之间的敏感性或特异性均无显著差异（=0.40，=0.065）。
VeriSee DR 适用于多种眼底彩色相机，在可评估性方面与眼科医生完全一致，对可转诊 DR 的诊断具有良好的敏感性和特异性。
