与安非他明（右苯丙胺 - 苯丙胺）及局部使用类固醇相关的中心性浆液性脉络膜视网膜病变

Central serous chorioretinopathy associated with Adderall (dextroamphetamine-amphetamine) and topical steroid use.

作者信息

Alsberge Joseph B, Lee Daniel Y, Jumper J Michael

机构信息

Department of Ophthalmology, Northwest Permanente, Portland, OR, USA.

West Coast Retina Medical Group, San Francisco, CA, USA.

出版信息

Am J Ophthalmol Case Rep. 2022 Mar 9;26:101482. doi: 10.1016/j.ajoc.2022.101482. eCollection 2022 Jun.

DOI:10.1016/j.ajoc.2022.101482

PMID:35308586

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8924628/

Abstract

PURPOSE

To report a case of central serous chorioretinopathy (CSC) associated with Adderall (dextroamphetamine-amphetamine) and topical steroid use.

OBSERVATIONS

A 34-year-old man presented for evaluation of a "cloud" in his vision for three months. He was taking Adderall for attention deficit hyperactivity disorder and mometasone 0.1% topical cream for eczema. He was found to have subretinal fluid in the left eye consistent with CSC. The subretinal fluid persisted despite cessation of the steroid cream but resolved after cessation of the Adderall. The subretinal fluid returned when the patient restarted Adderall and again resolved after he stopped it for a second time.

CONCLUSIONS

Though we cannot prove causality, the course of events was suggestive of a direct relationship between Adderall use and CSC in this patient, with exogenous steroid as a possible modifying factor.

摘要

目的

报告一例与安非他明（右苯丙胺 - 苯丙胺）及局部使用类固醇相关的中心性浆液性脉络膜视网膜病变（CSC）病例。

观察结果

一名34岁男性因视物有“云雾感”三个月前来就诊。他因注意力缺陷多动障碍服用安非他明，因湿疹使用0.1%的莫米松局部乳膏。检查发现其左眼存在与CSC相符的视网膜下液。尽管停用了类固醇乳膏，但视网膜下液仍持续存在，而停用安非他明后视网膜下液消退。当患者重新开始服用安非他明时，视网膜下液再次出现，在他再次停药后又消退。