Cohen Michelle, Nguyen Madeline, Nix Chad D, Case Brendan, Nickerson Joshua P, Bernard Jacqueline, Durrant Julia, Safarpour Delaram, Tucker Tarvez, Vagnerova Kamila, Messer William B
Department of Neurology, Oregon Health and Science University, Portland, OR, United States.
School of Medicine, Oregon Health and Science University, Portland, OR, United States.
Front Neurol. 2022 Feb 18;12:779014. doi: 10.3389/fneur.2021.779014. eCollection 2021.
Yellow fever vaccine-associated neurotropic disease (YEL-AND) is a rare and serious complication following vaccination with the 17D live attenuated yellow fever vaccine. Cases of YEL-AND have presented as acute inflammatory demyelinating polyneuropathy, acute disseminated encephalomyelitis, and meningoencephalitis. To date, intracranial imaging of the progression and resolution of this disease has been minimally depicted in the literature. We present the case of a 67-year-old woman who developed YEL-AND following vaccination. Her diagnosis was complicated by imaging findings consistent with variant Creutzfeldt Jakob Disease. Her clinical history and the progression of her intracranial imaging is discussed in this case report.
黄热病疫苗相关神经otropic疾病（YEL-AND）是接种17D减毒活黄热病疫苗后一种罕见且严重的并发症。YEL-AND病例表现为急性炎症性脱髓鞘性多发性神经病、急性播散性脑脊髓炎和脑膜脑炎。迄今为止，该疾病进展和消退的颅内影像学表现在文献中描述极少。我们报告一例67岁女性在接种疫苗后发生YEL-AND的病例。她的诊断因与变异型克雅氏病相符的影像学表现而复杂化。本病例报告讨论了她的临床病史及颅内影像学进展情况。
