Sharma Shikha, Roy Kallol Kumar, Rai Rakhi, Zangmo Rinchen, Malhotra Neena, Das Anamika
Department of Obstetrics and Gynecology, All India Institute of Medical Sciences, New Delhi, India.
Gynecol Minim Invasive Ther. 2022 Feb 14;11(1):41-46. doi: 10.4103/GMIT.GMIT_5_21. eCollection 2022 Jan-Mar.
Compare pain intensity at entry into the cervical os, during uterine distension and 15 min after the procedure, in patients undergoing diagnostic hysteroscopy with room temperature normal saline versus that with saline warmed to 38-40°C, using visual analog scale (VAS) score. Furthermore, compare the time taken and failed procedures between them.
This was a randomized controlled, prospective study conducted at a Tertiary Care Center on 100 patients planned for diagnostic hysteroscopy with a 4 mm 30° hysteroscope using vaginoscopy technique. They were divided into two groups of 50 each, with control undergoing the procedure using normal saline at room temperature and the test with saline warmed to 38-40°C as distension medium. Primary outcomes were VAS at the point of entry into the internal os (T0), 1 min later (T1), and 15 min after the procedure (T15). Secondary outcomes were procedural acceptance, time taken, and failed procedures.
The mean VAS in the control group at T0, T1, T15 was 3.31 (1.461;‒0.870-0.245), 2.46 (1.398;‒0.539-0.498), 0.75 (0.911;‒0.379-0.338), respectively, as compared to the test group of 3.62 (1.282;‒0.870-0.245), 2.48 (1.148;‒0.540-0.498), 0.77 (0.911;‒0.379-0.379), respectively. About 73.5% of controls and 68.8% in the test group were willing to undergo the procedure again. About 93.9% of controls would recommend it further as against 93.8% among the test controls. The time taken and number of failed procedures showed no statistical difference.
No significant difference was noted in terms of outcomes measured by warming the distension medium.
使用视觉模拟量表（VAS）评分，比较在诊断性宫腔镜检查中，使用室温生理盐水与38 - 40°C温热生理盐水的患者，在进入宫颈内口时、子宫扩张期间及术后15分钟的疼痛强度。此外，比较两组之间的操作时间和失败操作情况。
这是一项在三级医疗中心进行的随机对照前瞻性研究，对100例计划使用4mm 30°宫腔镜经阴道镜技术进行诊断性宫腔镜检查的患者进行研究。他们被分为两组，每组50人，对照组使用室温生理盐水进行操作，试验组使用加热至38 - 40°C的生理盐水作为扩张介质。主要结局指标为进入宫颈内口时（T0）、1分钟后（T1）及术后15分钟（T15）的VAS评分。次要结局指标为操作接受度、操作时间和失败操作情况。
对照组在T0、T1、T15时的平均VAS评分分别为3.31（1.461；-0.870 - 0.245）、2.46（1.398；-0.539 - 0.498）、0.75（0.911；-0.379 - 0.338），试验组分别为3.62（1.282；-0.870 - 0.245）、2.48（1.148；-0.540 - 0.498）、0.77（0.911；-0.379 - 0.379）。对照组约73.5%和试验组约68.8%的患者愿意再次接受该操作。对照组约93.9%的患者会进一步推荐该操作，试验组为93.8%。操作时间和失败操作数量无统计学差异。
在扩张介质加热方面，所测量的结局指标无显著差异。
