人淋巴细胞对沙眼衣原体的多克隆反应。
Polyclonal response of human lymphocytes to Chlamydia trachomatis.
作者信息
Räsänen L, Lehtinen M, Lehto M, Paavonen J, Leinikki P
出版信息
Infect Immun. 1986 Oct;54(1):28-31. doi: 10.1128/iai.54.1.28-31.1986.
Abstract
The mitogenicity of Chlamydia trachomatis was investigated. Umbilical cord blood cells from healthy newborns were used. These cells were stimulated in cultures with partially purified C. trachomatis elementary bodies. Proliferation of cultured lymphocytes and secreted immunoglobulins and leukocyte migration inhibitory factor were measured in the culture supernatants. Our results showed that C. trachomatis is able to elicit polyclonal antibody, lymphokine, and DNA synthesis.
摘要
研究了沙眼衣原体的促有丝分裂活性。使用了来自健康新生儿的脐带血细胞。这些细胞在培养物中用部分纯化的沙眼衣原体原体进行刺激。在培养上清液中测量培养淋巴细胞的增殖、分泌的免疫球蛋白和白细胞迁移抑制因子。我们的结果表明，沙眼衣原体能够引发多克隆抗体、淋巴因子和DNA合成。
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