眼科医生局部应用前列腺素类似物滴眼液后瞳孔间距缩短：一例报告
Shortening of interpupillary distance after topical prostaglandin analog eye drop application in an ophthalmic surgeon: A case report.
作者信息
Sano Ichiya, Takahashi Hidenori, Hara Takeshi, Kawashima Hidetoshi, Mayama Chihiro
机构信息
Department of Ophthalmology, Shimane University, 89-1, Enya Izumo Shimane, Japan.
Department of Ophthalmology, Jichi Medical University, 3311-1, Yakushiji Shimotsuke, Tochigi, Japan.
出版信息
Am J Ophthalmol Case Rep. 2022 Mar 15;26:101480. doi: 10.1016/j.ajoc.2022.101480. eCollection 2022 Jun.
PURPOSE
This study reports a case of interpupillary distance (IPD) shortening after instillation of topical prostaglandin analog (PGA) eye drops.
OBSERVATIONS
The patient was a 36-year-old ophthalmic vitreoretinal surgeon from Tochigi, Japan, with primary open-angle glaucoma and bilaterally instilled PGA eye drops to decrease intraocular pressure. His IPD had been recorded closely based on surgical microscope settings. The patient had a stable IPD for over five years before the use of PGA drops. The patient noticed IPD shortening associated with latanoprost usage since four years. The IPD shortened further twice with temporal switching to bimatoprost. However, the IPD partially recovered both the times on discontinuing the medication over the course of several months.
CONCLUSIONS AND IMPORTANCE
Fluctuations in IPD with visible cosmetic changes occur in association with the use of topical PGA eye drops. There might be effects of PGA drops on binocular vision, which are possibly unaddressed and warrant further study.
目的
本研究报告了一例局部使用前列腺素类似物（PGA）滴眼液后瞳孔间距（IPD）缩短的病例。
观察结果
该患者是一名来自日本枥木的36岁眼科玻璃体视网膜外科医生，患有原发性开角型青光眼，双侧滴用PGA滴眼液以降低眼压。其IPD已根据手术显微镜设置进行密切记录。在使用PGA滴眼液之前，患者的IPD在五年多的时间里保持稳定。自四年前起，患者注意到IPD缩短与使用拉坦前列素有关。改用比马前列素后，IPD又两次进一步缩短。然而，在停药数月后，IPD两次都部分恢复。
结论与重要性
使用局部PGA滴眼液会出现IPD波动并伴有明显的外观变化。PGA滴眼液可能对视双眼视觉有影响，这可能尚未得到解决，值得进一步研究。
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