School of Food Science and Pharmaceutical Engineering, Nanjing Normal University, Nanjing, 210023, People's Republic of China.
Anal Sci. 2022 Feb;38(2):339-346. doi: 10.2116/analsci.21P278. Epub 2022 Mar 22.
Bisphenol A (BPA) interferes with the reproduction and endocrine system of humans and wild animals. For the detection of BPA, a sensitive and rapid detection method was established. BPA was imprinted on the surface of FeO nanoparticles through dopamine self-polymerization. After the removal of BPA, molecularly imprinted microspheres with BPA recognition cavity were formed. The electrochemical impedance response increased with BPA embedded in the molecular imprinting layer. The electrochemical signal was proportional to the concentration of BPA with a linear range from 1 × 10 to 1 × 10 M and a detection limit of 5.78 × 10 M. The proposed biosensor was used to detect the BPA in vegetable oil indicating a promising application in food-field monitoring.
双酚 A（BPA）会干扰人类和野生动物的生殖和内分泌系统。为了检测 BPA，建立了一种灵敏快速的检测方法。通过多巴胺的自聚合作用，BPA 被印迹在 FeO 纳米粒子的表面。去除 BPA 后，形成具有 BPA 识别腔的分子印迹微球。随着 BPA 嵌入分子印迹层，电化学阻抗响应增加。电化学信号与 BPA 的浓度成正比，线性范围为 1×10 到 1×10−6 M，检测限为 5.78×10−6 M。该生物传感器用于检测植物油中的 BPA，表明其在食品领域监测方面具有广阔的应用前景。
