Operative Dentistry Department, Faculty of Dentistry, Mansoura University, Algomhoria St, Mansoura City, 35516, Egypt.
Dental Biomaterials Science Dept, Faculty of Dentistry, Mansoura University, Mansoura, Egypt.
Clin Oral Investig. 2022 May;26(5):3807-3822. doi: 10.1007/s00784-022-04449-2. Epub 2022 Mar 23.
To evaluate clinical performance of the new CAD/CAM resin-matrix ceramics and compare it with ceramic partial coverage restorations.
An electronic search of 3 databases (The National Library of Medicine (MEDLINE/PubMed), Scopus, and the Cochrane Central Register of Controlled Trials) was conducted. English clinical studies published between 2005 and September 2020 that evaluated the clinical performance of CAD/CAM resin-matrix ceramics inlays, onlays, or overlays were selected. The primary clinical question was applied according to PICOS strategy (Population, Intervention, Comparison, Outcome, Study design). The included studies were individually evaluated for risk of bias according to the modified Cochrane Collaboration tool criteria.
A total of 7 studies were included according to the established inclusion and exclusion criteria. From the included studies, 6 were randomized clinical trials while one study was longitudinal observational study without control group. According to the results of the included studies, the success rate of CAD/CAM resin-based composite ranged from 85.7 to 100% whereas the success rate reported for ceramic partial coverage restorations ranged from 93.3 to 100%. Fractures and debondings are found to be the most common cause of restorations failure.
CAD/CAM resin-based composite can be considered a reliable material for partial coverage restorations with clinical performance similar to glass ceramic restorations. However, this result needs to be confirmed in long-term evaluations.
CAD/CAM resin-based composites provide a potential alternative to ceramic indirect restorations. However, clinicians must be aware of the lake of knowledge regarding long-term outcome.
评估新型 CAD/CAM 树脂基质陶瓷的临床性能，并将其与陶瓷部分覆盖修复体进行比较。
对 3 个数据库（美国国立医学图书馆（MEDLINE/PubMed）、Scopus 和 Cochrane 对照试验中心注册库）进行电子检索。选择了 2005 年至 2020 年 9 月期间发表的评估 CAD/CAM 树脂基质陶瓷嵌体、高嵌体或贴面临床性能的英文临床研究。主要临床问题根据 PICOS 策略（人群、干预、比较、结局、研究设计）应用。根据改良 Cochrane 协作工具标准，对纳入的研究分别进行个体偏倚风险评估。
根据既定的纳入和排除标准，共纳入 7 项研究。纳入的研究中，有 6 项为随机临床试验，而 1 项为无对照组的纵向观察性研究。根据纳入研究的结果，CAD/CAM 树脂基复合材料的成功率为 85.7%至 100%，而陶瓷部分覆盖修复体的成功率为 93.3%至 100%。断裂和脱粘是导致修复体失败的最常见原因。
CAD/CAM 树脂基复合材料可被视为部分覆盖修复的可靠材料，其临床性能与玻璃陶瓷修复体相似。然而，这一结果需要在长期评估中得到证实。
CAD/CAM 树脂基复合材料为陶瓷间接修复体提供了一种潜在的替代方法。然而，临床医生必须意识到缺乏长期结果的相关知识。
