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呼吸道中免疫球蛋白对呼吸道合胞（RS）病毒感染细胞的包被。

The coating of respiratory syncytial (RS) virus-infected cells in the respiratory tract by immunoglobulins.

作者信息

Gardner P S, McQuillin J

出版信息

J Med Virol. 1978;2(2):165-73. doi: 10.1002/jmv.1890020211.

DOI:10.1002/jmv.1890020211
PMID:353227
Abstract

During the course of 26 respiratory syncytial (RS) virus infections, infected cells in the respiratory tract become coated with immunoglobulins (IgA, IgG, and IgM), IgA being predominant. Methods are described for detecting both intracellular virus and coating immunoglobulin using a double staining technique and immunofluorescence. IgA coating antibody appears in small amounts very early in the illness. The relationship of coating antibody to pathogenesis, prevention, and recovery from RS virus infection is discussed.

摘要

在26例呼吸道合胞（RS）病毒感染过程中，呼吸道中的受感染细胞被免疫球蛋白（IgA、IgG和IgM）覆盖，其中IgA占主导。本文描述了使用双重染色技术和免疫荧光检测细胞内病毒和覆盖免疫球蛋白的方法。IgA覆盖抗体在疾病早期就少量出现。本文还讨论了覆盖抗体与RS病毒感染的发病机制、预防及康复之间的关系。

相似文献

1
The coating of respiratory syncytial (RS) virus-infected cells in the respiratory tract by immunoglobulins.呼吸道中免疫球蛋白对呼吸道合胞（RS）病毒感染细胞的包被。
J Med Virol. 1978;2(2):165-73. doi: 10.1002/jmv.1890020211.
2
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引用本文的文献

1
Appearance of complement components and immunoglobulins on nasopharyngeal epithelial cells following naturally acquired infection with respiratory syncytial virus.呼吸道合胞病毒自然感染后鼻咽上皮细胞上补体成分和免疫球蛋白的出现情况。
J Med Virol. 1982;9(2):149-58. doi: 10.1002/jmv.1890090210.
2
In vitro cell-dependent lysis of respiratory syncytial virus-infected cells mediated by antibody from local respiratory secretions.由局部呼吸道分泌物中的抗体介导的呼吸道合胞病毒感染细胞的体外细胞依赖性裂解。
Clin Exp Immunol. 1981 Jan;43(1):28-35.
3
Complement fixing antibody responses to virus infection in children with acute lymphoblastic leukaemia.
急性淋巴细胞白血病患儿对病毒感染的补体结合抗体反应。
J Clin Pathol. 1980 Aug;33(8):735-7. doi: 10.1136/jcp.33.8.735.
4
Respiratory virus infection in hospitalized children in Austria 1979-1982. Diagnosis by immunofluorescence.1979 - 1982年奥地利住院儿童的呼吸道病毒感染。通过免疫荧光法诊断。
Infection. 1984 May-Jun;12(3):185-9. doi: 10.1007/BF01640896.
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Comparison of viral isolation, direct immunofluorescence, and indirect immunoperoxidase techniques for detection of genital herpes simplex virus infection.病毒分离、直接免疫荧光法和间接免疫过氧化物酶技术检测生殖器单纯疱疹病毒感染的比较
J Clin Microbiol. 1981 May;13(5):913-8. doi: 10.1128/jcm.13.5.913-918.1981.
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Respiratory syncytial virus. Brief review.呼吸道合胞病毒。简要综述。
Arch Virol. 1985;84(1-2):1-52. doi: 10.1007/BF01310552.
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Cell-free and cell-bound antibody in nasal secretions from infants with respiratory syncytial virus infection.呼吸道合胞病毒感染婴儿鼻分泌物中的游离抗体和结合细胞的抗体。
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