急性淋巴细胞白血病患儿的病毒感染
Virus infections in children with acute lymphoblastic leukaemia.
作者信息
Craft A W, Reid M M, Gardner P S, Jackson E, Kernahan J, McQuillin J, Noble T C, Walker W
出版信息
Arch Dis Child. 1979 Oct;54(10):755-9. doi: 10.1136/adc.54.10.755.
Abstract
The pattern of virus isolation and illness was studied in 64 children with acute lymphoblastic leukaemia (ALL) during periods of apparent infection and when the children were well. The virus isolation rate of 2.2 viruses per child a year is similar to that previously found in normal children. In only 32% of children with symptoms were viruses found and 14.5% had viruses isolated when asymptomatic. The children with ALL appear to be more vulnerable to multiple virus infections and to excrete the virus for longer periods. This may be due to failure of production of both local and systemic antibodies. The failure in the past to recognise the true importance of virus infections in ALL may have been due to inadequate diagnostic techniques.
摘要
对64名急性淋巴细胞白血病（ALL）患儿在明显感染期和病情缓解期的病毒分离情况及发病情况进行了研究。患儿每年人均病毒分离率为2.2种，这与之前在正常儿童中发现的情况相似。有症状的患儿中仅32%检测到病毒，无症状的患儿中有14.5%病毒分离呈阳性。ALL患儿似乎更容易受到多种病毒感染，且病毒排出时间更长。这可能是由于局部和全身抗体产生不足所致。过去未能认识到病毒感染在ALL中的真正重要性，可能是由于诊断技术不足。
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本文引用的文献
1
Amantadine therapy of epidemic influenza a(2) (Hong Kong).金刚烷胺治疗 A 型流感（香港）。
Infect Immun. 1970 Feb;1(2):200-4. doi: 10.1128/iai.1.2.200-204.1970.
2
3
The Virus Watch program: a continuing surveillance of viral infections in metropolitan New York families. 3. Preliminary report on association of infections with disease.
Am J Epidemiol. 1966 May;83(3):436-54. doi: 10.1093/oxfordjournals.aje.a120596.
4
Hematologic malignancies and other marrow failure states: progress in the management of complicating infections.血液系统恶性肿瘤及其他骨髓衰竭状态：并发感染的管理进展
Semin Hematol. 1974 Apr;11(2):141-202.
5
Rapid diagnosis of influenza by immunofluorescent techniques.通过免疫荧光技术快速诊断流感。
Lancet. 1970 Oct 3;2(7675):690-5. doi: 10.1016/s0140-6736(70)91961-6.
6
Influenza-A infection in children.儿童甲型流感感染
Lancet. 1972 Sep 9;2(7776):497-500. doi: 10.1016/s0140-6736(72)91902-2.
7
Viruses in families.病毒家族中的病毒。
Lancet. 1971 Apr 17;1(7703):769-74. doi: 10.1016/s0140-6736(71)91214-1.
8
Antibody response to poliovirus immunization in childhood leukemia.儿童白血病患者对脊髓灰质炎病毒免疫接种的抗体反应。
Med Pediatr Oncol. 1975;1(3):217-25. doi: 10.1002/mpo.2950010305.
9
Application of immunofluorescence to a study of measles.免疫荧光技术在麻疹研究中的应用。
Arch Dis Child. 1976 Jun;51(6):411-9. doi: 10.1136/adc.51.6.411.
10
The coating of respiratory syncytial (RS) virus-infected cells in the respiratory tract by immunoglobulins.呼吸道中免疫球蛋白对呼吸道合胞（RS）病毒感染细胞的包被。
J Med Virol. 1978;2(2):165-73. doi: 10.1002/jmv.1890020211.
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