Department of Dermatology, Henry Ford Health System, Detroit, MI, USA.
Int J Dermatol. 2023 May;62(5):589-598. doi: 10.1111/ijd.16160. Epub 2022 Mar 24.
Tranexamic acid is a plasmin inhibitor that is used off-label for the treatment of melasma. The use of tranexamic acid has expanded in the field of dermatology based on its anti-inflammatory and anti-melanin-producing properties, which include the treatment of rosacea, urticaria, and post-inflammatory hyperpigmentation. Tranexamic acid may have more uses in dermatology that require future studies. It should be used with caution during the COVID-19 pandemic given its procoagulant nature.
氨甲环酸是一种纤溶酶抑制剂，被超说明书用于治疗黄褐斑。基于其抗炎和抑制黑色素生成的特性，氨甲环酸在皮肤科领域的应用不断扩大，包括治疗酒渣鼻、荨麻疹和炎症后色素沉着过度。氨甲环酸在需要进一步研究的皮肤科领域可能有更多用途。鉴于其促凝特性，在 COVID-19 大流行期间应谨慎使用。
