Biondi Vito, Landi Alessandra, Pugliese Michela, Merola Giordana, Passantino Annamaria
Department of Veterinary Sciences, University of Messina, 98168 Messina, Italy.
Veterinary Practitioner, 98168 Messina, Italy.
Animals (Basel). 2022 Mar 19;12(6):778. doi: 10.3390/ani12060778.
This study aimed to evaluate possible abnormalities in electrocardiographic findings, and changes in cardiac troponin I (cTnI) and inflammatory biomarkers (serum amyloid A (SAA) and C-reactive protein (CRP)) after inactivated herpesvirus vaccine administration. Eighteen healthy horses were included. All animals were vaccinated with Pneumoequine (Merial, France) according to the protocol provided by the manufacturer. They were evaluated 1 day before the first dose of vaccination (D0), and 7 days (D1) and 14 days (D2) afterwards. At D0, D1, and D2, a blood sample was taken for the evaluation of SAA, cTnI, and CRP. An electrocardiographic examination was also performed. The data obtained suggested the possible involvement of the myocardium following vaccination against herpesvirus 1, mostly related to an inflammatory response.
本研究旨在评估灭活疱疹病毒疫苗接种后心电图检查结果可能存在的异常,以及心肌肌钙蛋白I(cTnI)和炎症生物标志物(血清淀粉样蛋白A(SAA)和C反应蛋白(CRP))的变化。纳入了18匹健康马匹。所有动物均按照制造商提供的方案接种了Pneumoequine(法国梅里亚公司)。在首次接种疫苗前1天(D0)、之后7天(D1)和14天(D2)对它们进行评估。在D0、D1和D2时,采集血样以评估SAA、cTnI和CRP。还进行了心电图检查。获得的数据表明,接种1型疱疹病毒疫苗后心肌可能受累,这主要与炎症反应有关。