Dempsey Tina, Nguyen Huong Lien, Nguyen Huong Thu, Bui Xuan Anh, Pham Phuong Thi Thu, Nguyen Toan K, Cavallin Francesco, Trevisanuto Daniele, Myrnerts Höök Susanna, Pejovic Nicolas, Blennow Mats, Olson Linus, Vu Hien, Nguyen Anh Duy, Alfvén Tobias
Department of Global Public Health, Karolinska Institutet, 17177 Solna, Sweden.
Astrid Lindgren Children's Hospital, Karolinska University Hospital, 17176 Solna, Sweden.
Children (Basel). 2022 Feb 28;9(3):321. doi: 10.3390/children9030321.
Every year, 2.4 million neonates die during their first month of life and even more suffer permanent injury. The main causes are intrapartum-related events, prematurity, and infection, with sub-Saharan Africa and southern Asia being the worst affected regions. With a focus on intrapartum-related events, we aimed to assess the neonatal demographic characteristics, clinical management, and outcomes among neonates born at the largest obstetric hospital in Hanoi, Vietnam. This was a retrospective cross-sectional study that included all the inborn neonates in November 2019, which was selected as a representative month. A total of 4554 neonates were born during the study period. Of these, 1.0% ( = 44) were stillbirths, 0.15% ( = 7) died in hospital, 0.61% ( = 28) received positive pressure ventilation at birth, and 0.15% ( = 7) were diagnosed with hypoxic ischemic encephalopathy. A total of 581 (13%) neonates were admitted to the neonatal unit, among which the most common diagnoses were prematurity (37%, = 217) and infection (15%, = 89). Except for the intrapartum-related events, our findings are consistent with the previously documented data on neonatal morbidity. The intrapartum-related events, however, were surprisingly low in number even in comparison to high-income countries. Research on the current clinical practice at Phu San Hanoi Hospital may bring further clarity to identify the success factors.
每年有240万新生儿在出生后的第一个月内死亡,更多的新生儿遭受永久性损伤。主要原因是分娩期相关事件、早产和感染,撒哈拉以南非洲和南亚地区受影响最为严重。以分娩期相关事件为重点,我们旨在评估越南河内最大的产科医院出生的新生儿的人口统计学特征、临床管理及结局。这是一项回顾性横断面研究,纳入了2019年11月所有的院内出生新生儿,该月被选为代表月。研究期间共出生4554名新生儿。其中,1.0%(n = 44)为死产,0.15%(n = 7)在医院死亡,0.61%(n = 28)出生时接受了正压通气,0.15%(n = 7)被诊断为缺氧缺血性脑病。共有581名(13%)新生儿入住新生儿病房,其中最常见的诊断是早产(37%,n = 217)和感染(15%,n = 89)。除分娩期相关事件外,我们的研究结果与先前记录的新生儿发病率数据一致。然而,即使与高收入国家相比,分娩期相关事件的数量也出奇地低。对河内富山医院当前临床实践的研究可能会进一步明确成功因素。