Department of Oral Medicine and Stomatology, Tsurumi University School of Dental Medicine, 2-1-3 Tsurumi, Tsurumi-ku, Kanagawa, Yokohama 230-8501, Japan.
Choetsu Kaken Co., Ltd., 1-1-40 Suehiro-cho, Tsurumi-ku, Kanagawa, Yokohama 230-0045, Japan.
Int J Environ Res Public Health. 2022 Mar 18;19(6):3639. doi: 10.3390/ijerph19063639.
Masks are effective for preventing the spread of COVID-19 and other respiratory infections. If antimicrobial properties can be applied to the non-woven fabric filters in masks, they can become a more effective countermeasure against human-to-human and environmental infections. We investigated the possibilities of carrying antimicrobial agents on the fiber surfaces of non-woven fabric filters by applying silica-resin coating technology, which can form silica-resin layers on such fabrics at normal temperature and pressure. Scanning electron microscopy and electron probe microanalysis showed that a silica-resin layer was formed on the fiber surface of non-woven fabric filters. Bioassays for coronavirus and quantitative reverse transcription-polymerase chain reactions (RT-PCR) revealed that all antimicrobial agents tested loaded successfully onto non-woven fabric filters without losing their inactivation effects against the human coronavirus (inhibition efficacy: >99.999%). These results indicate that this technology could be used to load a functional substance onto a non-woven fabric filter by vitrifying its surface. Silica-resin coating technology also has the potential of becoming an important breakthrough not only in the prevention of infection but also in various fields, such as prevention of building aging, protection of various cultural properties, the realization of a plastic-free society, and prevention of environmental pollution.
口罩对于预防 COVID-19 和其他呼吸道传染病的传播非常有效。如果能将抗菌性能应用于口罩的无纺纤维滤材上,那么口罩将成为对抗人际间和环境感染的更有效对策。我们研究了通过应用常温常压下能在纤维表面形成硅树脂层的硅树脂涂层技术,将抗菌剂负载于无纺纤维滤材纤维表面的可能性。扫描电子显微镜和电子探针微量分析表明,硅树脂层形成于无纺纤维滤材的纤维表面。针对冠状病毒的生物测定和定量逆转录聚合酶链反应(RT-PCR)显示,所有测试的抗菌剂都成功地负载于无纺纤维滤材上,而不会失去其对人冠状病毒的灭活效果(抑制效率:>99.999%)。这些结果表明,该技术可以通过使表面玻璃化将功能物质负载于无纺纤维滤材上。硅树脂涂层技术不仅在预防感染方面,而且在建筑老化预防、各种文化财产保护、实现无塑料社会以及环境污染预防等各个领域都具有成为重要突破的潜力。