Salam Amar M, Salim Imtiaz, Kaddoura Rasha, Singh Rajvir, Asaad Nidal, Al-Qahtani Awad, Al Suwaidi Jassim, AlBinali Hajar A
Department of Cardiology, Al-Khor Hospital, Hamad Medical Corporation, Doha, Qatar.
Department of Cardiology, Heart Hospital, Hamad Medical Corporation, Doha, Qatar.
Heart Views. 2021 Oct-Dec;22(4):256-263. doi: 10.4103/HEARTVIEWS.HEARTVIEWS_33_21. Epub 2022 Feb 11.
The vast majority of literature on atrial fibrillation (AF) is based on studies from the developed world that mainly includes Caucasian patients. Data on AF in other ethnicities is very limited. The aim of this hospital-based study is to evaluate the effect of concomitant hypertension (HTN) on the characteristics and outcomes of Middle Eastern Arab and South Asian patients with AF in the state of Qatar.
During the 20-year period, 3850 AF patients were hospitalized; 1483 (38.5%) had HTN, and 2367 (61.5%) without HTN. Patients with HTN were 11 years older, compared to non-HTN patients, and had a significantly higher prevalence of diabetes mellitus, chronic kidney disease, and dyslipidemia, compared to non-HTN patients. Furthermore, underlying coronary artery disease and heart failure were significantly more common but not valvular and rheumatic heart diseases which were more common in those without HTN. The rates of in-hospital mortality and stroke were significantly higher in the presence of HTN (5.3% versus 3.5%, and 0.7% versus 0.2% respectively, = 0.001), compared to non-HTN patients.
HTN is significantly associated with more comorbidities and worse clinical outcomes when it coexists with AF in hospitalized Middle Eastern Arab and South Asian patients.
绝大多数关于心房颤动（AF）的文献基于来自发达国家的研究，这些研究主要纳入高加索患者。关于其他种族AF的数据非常有限。这项基于医院的研究旨在评估合并高血压（HTN）对卡塔尔境内中东阿拉伯和南亚AF患者的特征及预后的影响。
在这20年期间，3850例AF患者住院治疗；1483例（38.5%）患有HTN，2367例（61.5%）未患HTN。与未患HTN的患者相比，患HTN的患者年龄大11岁，且糖尿病、慢性肾脏病和血脂异常的患病率显著更高。此外，潜在的冠状动脉疾病和心力衰竭明显更常见，但瓣膜性和风湿性心脏病在未患HTN的患者中更常见。与未患HTN的患者相比，存在HTN时院内死亡率和卒中发生率显著更高（分别为5.3%对3.5%，0.7%对0.2%，P = 0.001）。
在住院的中东阿拉伯和南亚患者中，当HTN与AF共存时，HTN与更多合并症及更差的临床预后显著相关。
