Nuwairan Muneerah Al, Souayeh Basma
Department of Mathematics and Statistics, College of Science, King Faisal University, P.O. Box 400, Al-Ahsa 31982, Saudi Arabia.
Department of Physics, College of Science, King Faisal University, P.O. Box 400, Al-Ahsa 31982, Saudi Arabia.
Micromachines (Basel). 2022 Feb 26;13(3):374. doi: 10.3390/mi13030374.
The study of gold nanoparticles (AuNPs) in the blood flow has emerged as an area of interest for numerous researchers, due to its many biomedical applications, such as cancer radiotherapy, DNA and antigens, drug and gene delivery, in vitro evaluation, optical bioimaging, radio sensitization and laser phototherapy of cancer cells and tumors. Gold nanoparticles can be amalgamated in various shapes and sizes. Due to this reason, gold nanoparticles can be diffused efficiently, target the diseased cells and destroy them. The current work studies the effect of gold nanoparticles of different shapes on the electro-magneto-hydrodynamic (EMHD) peristaltic propulsion of blood in a micro-channel under various effects, such as activation energy, bioconvection, radiation and gyrotactic microorganisms. Four kinds of nanoparticle shapes, namely bricks, cylinders and platelets, are considered. The governing equations are simplified under the approximations of low Reynolds number (LRN), long wavelength (LWL) and Debye-Hückel linearization (DHL). The numerical solutions for the non-dimensional equations are solved using the computational software MATLAB with the help of the bvp4c function. The influences of different physical parameters on the flow and thermal characteristics are computed through pictorial interpretations.
由于金纳米颗粒（AuNPs）在许多生物医学应用中具有重要作用，如癌症放射治疗、DNA和抗原、药物和基因递送、体外评估、光学生物成像、放射增敏以及癌细胞和肿瘤的激光光疗等，因此对其在血流中的研究已成为众多研究人员感兴趣的领域。金纳米颗粒可以制成各种形状和尺寸。基于此，金纳米颗粒能够有效扩散，靶向病变细胞并将其破坏。当前的研究工作考察了在活化能、生物对流、辐射和趋旋微生物等各种效应下，不同形状的金纳米颗粒对微通道中血液的电磁流体动力学（EMHD）蠕动推进的影响。研究考虑了四种纳米颗粒形状，即砖形、圆柱形和血小板形。在低雷诺数（LRN）、长波长（LWL）和德拜 - 休克尔线性化（DHL）近似下对控制方程进行了简化。使用计算软件MATLAB借助bvp4c函数求解无量纲方程的数值解。通过图形解释计算了不同物理参数对流动和热特性的影响。
