Michel Jean-Pierre, Frangos Emilia
Département de Réhabilitation et Gériatrie, Hôpitaux Universitaires de Genève, 1226 Geneva, Switzerland.
Vaccines (Basel). 2022 Mar 11;10(3):431. doi: 10.3390/vaccines10030431.
Mean longevity is increasing worldwide, with major consequences for public health worldwide, as the global population of adults aged over 65 years now exceeds the number of children under 5 for the first time in history. The ageing process over the life course is extremely heterogeneous, and it will be important to promote and enhance healthy ageing worldwide. Vaccination is a key player in the healthy ageing process, both at the individual and the community level. We review here the contribution of vaccines to individual and community health. At an individual level, we highlight the prevention of infectious diseases, as well as other, less well-known benefits of vaccination, such as modulation of the inflammatory process. We then underline the importance of vaccination in achieving herd immunity and reducing the transmission of pathogens in the community. Finally, at a community level, another important benefit of vaccination is the reduction in antimicrobial resistance. Taken together, these effects contribute to ensuring the best health, for the greatest number, for the longest time possible.
全球平均寿命正在延长，这对全球公共卫生产生了重大影响，因为65岁以上的全球成年人口数量目前有史以来首次超过了5岁以下儿童的数量。一生中的衰老过程极为不均一，在全球范围内促进和加强健康老龄化将非常重要。疫苗接种在健康老龄化过程中，无论是在个人层面还是社区层面，都起着关键作用。我们在此回顾疫苗对个人和社区健康的贡献。在个人层面，我们强调传染病的预防，以及疫苗接种的其他鲜为人知的益处，如调节炎症过程。然后，我们强调疫苗接种在实现群体免疫和减少社区内病原体传播方面的重要性。最后，在社区层面，疫苗接种的另一个重要益处是减少抗菌药物耐药性。综上所述，这些作用有助于尽可能长时间地确保最大数量的人享有最佳健康。
