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()Bonpl. 的类黄酮苷、三萜、挥发性化合物和抗菌活性()。

Flavanone Glycosides, Triterpenes, Volatile Compounds and Antimicrobial Activity of (Bonpl.) DC. ().

机构信息

Programa de Pós-Graduação em Química, Universidade Federal do Pará, Avenida Augusto Corrêa 01, Belém 66075-110, PA, Brazil.

Laboratório Adolpho Ducke, Coordenação de Botânica, Museu Paraense Emílio Goeldi, Avenida Perimetral, 1901, Belém 66077-830, PA, Brazil.

出版信息

Molecules. 2022 Mar 21;27(6):2005. doi: 10.3390/molecules27062005.

Abstract

Chemical composition of the essential oils and extracts and the antimicrobial activity of Miconia minutiflora were investigated. The flavanone glycosides, pinocembroside and pinocembrin-7-O-[4″,6″-HHDP]-β-D-glucose, were identified, along with other compounds that belong mainly to the triterpene class, besides the phenolics, gallic acid and methyl gallate. Sesquiterpenes and monoterpenes were the major compounds identified from the essential oils. Screening for antimicrobial activity from the methanolic extract of the leaves showed that the MIC and MMC values against the tested microorganisms ranged from 0.625 to 5 mg·mL−1 and that the extract was active against microorganisms, Staphyloccocus aureus, Escherichia coli, and Bacillus cereus.

摘要

对小蔓长春花的精油和提取物的化学成分及其抗菌活性进行了研究。鉴定了黄酮苷 pinocembroside 和 pinocembrin-7-O-[4″,6″-HHDP]-β-D-葡萄糖,以及其他主要属于三萜类化合物的化合物,此外还有酚类、没食子酸和甲基没食子酸。从叶子的甲醇提取物中鉴定出的主要化合物为倍半萜和单萜。对甲醇提取物的抗菌活性进行筛选,结果表明其对测试微生物的 MIC 和 MMC 值范围为 0.625 至 5mg·mL−1,并且该提取物对金黄色葡萄球菌、大肠杆菌和蜡样芽孢杆菌具有活性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fe23/8954877/7a1e9ab07749/molecules-27-02005-g001.jpg

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