Thatcher W W, Bazer F W, Sharp D C, Roberts R M
J Anim Sci. 1986;62 Suppl 2:25-46. doi: 10.1093/ansci/62.2.25.
Processes associated with "Maternal Recognition of Pregnancy" are reviewed extensively from the ovine, bovine, porcine and equine species. Comparisons among these species indicate that CL maintenance is achieved primarily by a predominant antiluteolytic-anti PGF effect, and there is strong evidence for antiluteolytic-luteoprotective and luteotropic controls that complement this basic system. The nature of the chemical signals (steroids, prostaglandins and proteins) to regulate these processes among the species are described. Common to all of the species reviewed is a change in vascular dynamics to and from the uterus and ovary during early pregnancy. The dialogue between endometrial epithelium and trophectoderm of the developing conceptus is described. The consequence of these various physiological and biochemical responses of early pregnancy is maintenance of the CL to provide a sustained embryotrophic environment. Either in the absence of or death of a conceptus, an efficient and acute system is operational to terminate this progestational environment via regression of the CL through uterine production of PGF.
本文广泛回顾了绵羊、牛、猪和马等物种中与“母体妊娠识别”相关的过程。这些物种之间的比较表明，黄体的维持主要是通过占主导地位的抗溶黄体 - 抗前列腺素F2α作用实现的，并且有强有力的证据表明存在抗溶黄体 - 黄体保护和促黄体生成素控制，它们对这个基本系统起到补充作用。文中描述了调节这些物种间过程的化学信号（类固醇、前列腺素和蛋白质）的性质。所有被回顾的物种在妊娠早期子宫和卵巢之间的血管动力学都会发生变化。文中还描述了发育中孕体的子宫内膜上皮与滋养外胚层之间的对话。妊娠早期这些各种生理和生化反应的结果是维持黄体，以提供持续的胚胎营养环境。在没有孕体或孕体死亡的情况下，一个高效且快速的系统会通过子宫产生前列腺素F2α使黄体退化，从而终止这种孕激素环境。
