Centor R M, Dalton H P, Campbell M S, Lynch M R, Watlington A T, Garner B K
J Gen Intern Med. 1986 Jul-Aug;1(4):248-51. doi: 10.1007/BF02596194.
A rapid latex agglutination slide test for group A beta-hemolytic streptococcal throat infections was prospectively evaluated. Resident physicians, working in an adult non-acute emergency room, recorded clinical data and collected throat swabs from 729 adult patients with sore throats. Research assistants obtained throat swabs from 329 control patients. Sensitivity and specificity, compared with routine cultures, were 96% and 97%, respectively. Analyses of clinical predictions and of test results for control patients, however, suggest that this test may perform better than routine culture. The test provides a rapid, accurate, potentially useful alternative for diagnosing group A beta-hemolytic streptococcal pharyngitis in adults.
对一种用于检测 A 组β溶血性链球菌咽喉感染的快速乳胶凝集玻片试验进行了前瞻性评估。在成人非急性急诊室工作的住院医师记录了临床数据，并从 729 例咽痛成年患者中采集了咽喉拭子。研究助手从 329 例对照患者中采集了咽喉拭子。与常规培养相比，该试验的敏感性和特异性分别为 96%和 97%。然而，对临床预测和对照患者检测结果的分析表明，该试验可能比常规培养表现更好。该试验为诊断成人 A 组β溶血性链球菌咽炎提供了一种快速、准确且可能有用的替代方法。
