一种用于快速诊断A组链球菌的新型乳胶凝集试验。
A new latex agglutination test for rapid diagnosis of group A streptococci.
作者信息
Fujikawa S, Ohkuni M
出版信息
Jpn Circ J. 1986 Dec;50(12):1251-2. doi: 10.1253/jcj.50.1251.
A rapid diagnostic test for group A streptococci from throat swabs (Culturette Brand 10-Min Strep ID test of Marion Inc.) was performed in 210 patients with acute pharyngitis. This agglutination test is based on the extraction of streptococcal polysaccharide by nitrous acid and observe agglutination with anti-polysaccharide-coated latex suspension. There was a 95.2% total agreement with a standard culture method and agglutination test and specificity of 93.4%, sensitivity of 96.0% positive predictive value of 90.5% and negative predictive value of 97.3%. From the results of our study, the agglutination test for group A streptococci is of diagnostic value. This new kit would be most useful in out-patient clinics, especially in a small private medical office without culture facilities.
对210例急性咽炎患者进行了用咽喉拭子检测A组链球菌的快速诊断试验（Marion公司Culturette品牌10分钟链球菌鉴定试验）。该凝集试验基于用亚硝酸提取链球菌多糖，并观察其与抗多糖包被乳胶悬液的凝集情况。与标准培养方法相比，凝集试验的总体符合率为95.2%，特异性为93.4%，敏感性为96.0%，阳性预测值为90.5%，阴性预测值为97.3%。根据我们的研究结果，A组链球菌凝集试验具有诊断价值。这种新试剂盒在门诊诊所，尤其是在没有培养设施的小型私人医疗诊所中最为有用。
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