Rattananukrom Teerapong, Suchonwanit Poonkiat, Thadanipon Kunlawat, Vachiramon Vasanop
All authors are with the Division of Dermatology, Faculty of Medicine, Ramathibodi Hospital at Mahidol University in Bangkok, Thailand.
Dr. Thadanipon is also with the Department of Clinical Epidemiology and Biostatistics, Faculty of Medicine, Ramathibodi Hospital at Mahidol University in Bangkok, Thailand.
J Clin Aesthet Dermatol. 2022 Mar;15(3):16-20.
Dermatoscopy is a noninvasive diagnostic tool for pigmented lesions. However, data regarding dermatoscopic features in melasma and Hori's nevus, which are commonly found in Asian populations, are still lacking. In addition, melasma coexisting with Hori's nevus presents a particular diagnostic challenge and they generally require different treatments.
We sought to describe the dermatoscopic features of melasma and Hori's nevus and to establish diagnostic clues for each condition.
Fifty patients with melasma and 46 patients with Hori's nevus were enrolled in the study. Dermatoscopic pictures were taken with Dermlite DL200 HR (3Gen, San Juan Capistrano, Califorinia) and evaluated by two blinded board-certified dermatologists.
The dermatoscopic features more prominently seen in melasma compared to Hori's nevus include light brown pigmentation (98% vs. 10.9%, <0.001), regular pigment network (38% vs. 2.2%, <0.001), irregular pigment network (98% vs. 63%, <0.001), arcuate structure (68% vs. 13%, <0.001), circles (48% vs. 10.9%, <0.001), sparing of follicles and sweat gland openings (98% vs. 4.3%, <0.001), and telangiectasias (52% vs. 19.6%, =0.001). In contrast, the common features of Hori's nevus include blue-brown or grey pigmentation (63% vs. 0%, =0.001) and speckled homogenous pattern (52.2% vs. 0%, P<0.001).
Dermatoscopy is a useful diagnostic tool for distinguishing between melasma and Hori's nevus. In patients with coexistence of both conditions, dermatoscopy can be used to confirm the diagnosis and aid the proper treatment.
皮肤镜检查是一种用于色素沉着性病变的非侵入性诊断工具。然而，关于黄褐斑和太田痣（在亚洲人群中常见）的皮肤镜特征的数据仍然缺乏。此外，黄褐斑与太田痣并存带来了特殊的诊断挑战，且它们通常需要不同的治疗方法。
我们试图描述黄褐斑和太田痣的皮肤镜特征，并为每种情况建立诊断线索。
本研究纳入了50例黄褐斑患者和46例太田痣患者。使用Dermlite DL200 HR（3Gen，加利福尼亚州圣胡安卡皮斯特拉诺）拍摄皮肤镜图像，并由两名不知情的皮肤科专科医生进行评估。
与太田痣相比，黄褐斑中更显著的皮肤镜特征包括浅棕色色素沉着（98%对10.9%，<0.001）、规则色素网（38%对2.2%，<0.001）、不规则色素网（98%对63%，<0.001）、弓形结构（68%对13%，<0.001）、圆圈（48%对10.9%，<0.001）、毛囊和汗腺开口 sparing（98%对4.3%，<0.001）以及毛细血管扩张（52%对19.6%，=0.001）。相比之下，太田痣的常见特征包括蓝棕色或灰色色素沉着（63%对0%，=0.001）和斑点状均匀模式（52.2%对0%，P<0.001）。
皮肤镜检查是区分黄褐斑和太田痣的有用诊断工具。对于两种情况并存的患者，皮肤镜检查可用于确诊并辅助适当的治疗。
