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钾钛磷激光与平阳霉素治疗成人喉部血管瘤的比较。

A Comparison of Potassium Titanyl Phosphate Laser and Pingyangmycin as Treatment for Adult Laryngeal Hemangioma.

机构信息

Department of Otolaryngology-Head and Neck Surgery, Eye, Ear, Nose & Throat Hospital, Fudan University, Shanghai, PR China.

Departments of Laser Plastic Surgery, Eye, Ear, Nose & Throat Hospital, Fudan University, Shanghai, PR China.

出版信息

Ear Nose Throat J. 2024 Dec;103(12):NP749-NP755. doi: 10.1177/01455613221086534. Epub 2022 Mar 28.

DOI:10.1177/01455613221086534
PMID:35345911
Abstract

: To evaluate the curative effect of Potassium titanyl phosphate (KTP) laser and pingyangmycin injection for adult laryngeal hemangiomas (ALH). : This was a retrospective study conducted on patients treated with either KTP laser or pingyangmycin injection to assess the efficacy of both treatment and compare the effects on different types of adult laryngeal hemangioma. : The ordinal logistic regression test showed the surgery methods had no effect on the therapeutic results. On the contrary, the shape of ALH and the interaction between surgical procedures and ALH shape affected the prognosis of the ALH. This meant that the shape of ALH might be a confounding factor affecting the therapeutic effect of ALH. Thus, the Cochran-Mantel-Haenszel test which is a stratification analysis was used to assess the interaction between surgical procedures and ALH shape. Then better results were achieved using the KTP laser for the plane and raised types of ALH. : The selection of surgical procedures (the KTP laser or pingyangmycin injection approaches) affects the treatment of ALH. For plane and raised ALH, the KTP laser may be recommended.

摘要

评估钛酸钾磷(KTP)激光和平阳霉素注射治疗成人喉血管瘤(ALH)的疗效。

这是一项回顾性研究,对接受 KTP 激光或平阳霉素注射治疗的患者进行评估,以评估两种治疗方法的疗效,并比较它们对不同类型成人喉血管瘤的影响。

有序逻辑回归检验表明手术方法对治疗结果没有影响。相反,ALH 的形状以及手术程序和 ALH 形状之间的相互作用影响了 ALH 的预后。这意味着 ALH 的形状可能是影响 ALH 治疗效果的混杂因素。因此,采用 Cochran-Mantel-Haenszel 检验进行分层分析,以评估手术程序和 ALH 形状之间的相互作用。然后,对于平面和隆起型 ALH,使用 KTP 激光取得了更好的效果。

手术程序(KTP 激光或平阳霉素注射方法)的选择影响 ALH 的治疗。对于平面和隆起型 ALH,推荐使用 KTP 激光。

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